SCHEMBL29958743

SCHEMBL29958743

CC(C)(C)OC(=O)/N=C(/NCCc1c[nH]c2ccc(O)cc12)NC(=O)OC(C)(C)C

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SPR P35270 4/20 0.58
KDM4E B2RXH2 3/20 0.58
ALDH1A1 P00352 2/20 0.58
NPSR1 Q6W5P4 2/20 0.58
CYP2D6 P10635 2/20 0.58
CYP1A2 P05177 1/20 0.58
CYP3A4 P08684 1/20 0.58
MAPT P10636 1/20 0.58
IDO1 P14902 1/20 0.58
HPGD P15428 1/20 0.58
BLM P54132 1/20 0.58
NOTUM Q6P988 1/20 0.58
TRPV1 Q8NER1 5/20 0.57
LMNA P02545 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
MEN1 O00255 1/20 0.51
HTR2C P28335 1/20 0.51
KMT2A Q03164 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16216347 1.00 SPR (0.58) SPRKDM4EALDH1A1NPSR1CYP2D6
SCHEMBL16208899 0.92 SPR (0.58) SPRKDM4EALDH1A1NPSR1CYP2D6
SCHEMBL16208898 0.92 SPR (0.58) SPRKDM4EALDH1A1NPSR1CYP2D6
SCHEMBL798165 0.86 TRPV1 (0.70) SPRKDM4EALDH1A1NPSR1CYP2D6
SCHEMBL31077788 0.86 TRPV1 (0.70) SPRKDM4EALDH1A1NPSR1CYP2D6
SCHEMBL16216349 0.85 MTNR1A (0.58) KDM4EALDH1A1CYP2D6CYP1A2CYP3A4
SCHEMBL2534000 0.78 TYR (0.62) SPRKDM4EALDH1A1NPSR1CYP2D6
SCHEMBL20182380 0.78 SPR (0.64) SPRKDM4EALDH1A1NPSR1CYP2D6
SCHEMBL28829086 0.78 SPR (0.64) SPRKDM4EALDH1A1NPSR1CYP2D6
SCHEMBL29616348 0.78 SPR (0.64) SPRKDM4EALDH1A1NPSR1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250170282-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. (US) 2025-05-29 US disclosed
US-20220339303-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. 2022-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250170282-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS FABP3, TNNI3, TNNT2 SPR 3634/4885KDM4E 3637/4885ALDH1A1 2699/4885
US-20220339303-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS FABP3, TNNI3, TNNT2 SPR 3634/4885KDM4E 3637/4885ALDH1A1 2699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.