SCHEMBL29958746

SCHEMBL29958746

CNC(=O)NCc1ccccc1-c1ccc(CN2C(=O)[C@H](NC(=O)CC(C)(C)N)CCc3ccccc32)cc1

nearest known ligand 0.84

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 4/20 0.84
AGTR1 P30556 1/20 0.66
XIAP P98170 12/20 0.54
NPY1R P25929 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7785968 1.00 GHSR (0.84) GHSRAGTR1XIAPNPY1R
SCHEMBL7785910 0.93 GHSR (0.84) GHSRAGTR1XIAPNPY1R
SCHEMBL7794454 0.93 GHSR (0.85) GHSRAGTR1XIAPNPY1R
SCHEMBL9024983 0.92 GHSR (0.72) GHSRAGTR1XIAPNPY1R
SCHEMBL7791646 0.92 GHSR (0.72) GHSRAGTR1XIAPNPY1R
SCHEMBL7438263 0.92 GHSR (1.00) GHSRAGTR1XIAPNPY1R
SCHEMBL7786019 0.91 GHSR (0.80) GHSRAGTR1XIAPNPY1R
SCHEMBL7791981 0.91 GHSR (0.71) GHSRAGTR1XIAPNPY1R
SCHEMBL7791707 0.91 GHSR (0.70) GHSRAGTR1XIAPNPY1R
SCHEMBL9024490 0.90 GHSR (0.69) GHSRAGTR1XIAPNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260077018-A1 TREATMENT OF MILD TRAUMATIC BRAIN INJURY OXEIA BIOPHARMACEUTICALS INC (US) 2026-03-19 US disclosed
EP-4583902-A2 TREATMENT OF MILD TRAUMATIC BRAIN INJURY Oxeia Biopharmaceuticals, Inc. (US) 2025-07-16 EP disclosed
WO-2024054875-A2 TREATMENT OF MILD TRAUMATIC BRAIN INJURY OXEIA BIOPHARMACEUTICALS, INC. (US) 2024-03-14 WO disclosed
US-20230330187-A1 USE OF GHRELIN OR GHRELIN VARIANT FOR INCREASING DOSE INTENSITY OF CHEMOTHERAPEUTIC AGENTS IN PATIENTS WITH CANCER OXEIA BIOPHARMACEUTICALS INC (US) 2023-10-19 US disclosed
WO-2022226116-A1 GHRELIN TREATMENT OF BRAIN DYSFUNCTION DUE TO VIRAL INFECTION OXEIA BIOPHARMACEUTICALS, INC. (US) 2022-10-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260077018-A1 TREATMENT OF MILD TRAUMATIC BRAIN INJURY CRH, MYO1G, GHRHR GHSR 6/4885AGTR1 4140/4885XIAP 2581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.