SCHEMBL29959883

SCHEMBL29959883

CCOC(=O)C=C1CCOc2cccc(F)c21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTDSP1 Q9GZU7 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
SMN1; SMN2 Q16637 3/20 0.36
RAB9A P51151 5/20 0.36
NPC1 O15118 4/20 0.36
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 1/20 0.36
GLA P06280 2/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
ATM Q13315 1/20 0.35
ESR2 Q92731 1/20 0.35
PKM P14618 1/20 0.35
NLRP3 Q96P20 1/20 0.34
MTNR1B P49286 1/20 0.34
L3MBTL1 Q9Y468 3/20 0.34
NOTUM Q6P988 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7942826 0.81 CTDSP1 (0.47) CTDSP1TDP1SMN1; SMN2RAB9ANPC1
SCHEMBL1826971 0.81 CTDSP1 (0.47) CTDSP1TDP1SMN1; SMN2RAB9ANPC1
SCHEMBL29961371 0.80 CTDSP1 (0.43) CTDSP1TDP1RAB9ANPC1ALDH1A1
SCHEMBL5480595 0.80 CTDSP1 (0.43) CTDSP1TDP1RAB9ANPC1ALDH1A1
SCHEMBL10463565 0.80 CTDSP1 (0.43) CTDSP1TDP1RAB9ANPC1ALDH1A1
SCHEMBL10407756 0.76 CTDSP1 (0.40) CTDSP1TDP1SMN1; SMN2RAB9ANPC1
SCHEMBL23117243 0.72 TDP1 (0.51) CTDSP1TDP1RAB9ANPC1ALDH1A1
SCHEMBL31021614 0.71 ALDH1A1 (0.39) CTDSP1TDP1SMN1; SMN2RAB9ANPC1
SCHEMBL10407623 0.71 USP2 (0.41) CTDSP1TDP1SMN1; SMN2RAB9ANPC1
SCHEMBL24867670 0.71 ALDH1A1 (0.39) CTDSP1TDP1SMN1; SMN2RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022204150-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS BLUE OAK PHARMACEUTICALS, INC. (US) 2022-09-29 WO disclosed