Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | ACACB | O00763 | 5/20 | 0.36 |
| ▸ | ACACA | Q13085 | 3/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.33 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14906835 | 0.80 | DRD2 (0.42) | LMNADRD2ACACBACACASPR | |
| SCHEMBL29960403 | 0.77 | ACACB (0.38) | DRD2ACACBACACASPRCKS1B | |
| SCHEMBL29960757 | 0.76 | ACACB (0.39) | GAAALDH1A1DRD2ACACBACACA | |
| SCHEMBL29960814 | 0.69 | ACACB (0.39) | GAAALDH1A1DRD2ACACBACACA | |
| SCHEMBL12644515 | 0.68 | TAAR1 (0.59) | GAAALDH1A1LMNADRD2MAPT | |
| SCHEMBL29959709 | 0.67 | ACACB (0.36) | GAALMNADRD2ACACBACACA | |
| SCHEMBL29960238 | 0.67 | DRD2 (0.39) | DRD2ACACBACACACKS1BSKP1 | |
| SCHEMBL29960245 | 0.67 | BRD4 (0.41) | ALDH1A1LMNADRD2ACACBSPR | |
| SCHEMBL14906836 | 0.66 | DRD2 (0.38) | ALDH1A1DRD2ACACBACACAEPHX1 | |
| SCHEMBL388481 | 0.66 | ESR1 (0.48) | DRD2ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |