Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 9/20 | 0.38 |
| ▸ | ACACA | Q13085 | 5/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP1 | P63208 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14906835 | 0.81 | DRD2 (0.42) | ACACBACACADRD2CKS1BSKP1 | |
| SCHEMBL29960757 | 0.78 | ACACB (0.39) | ACACBACACADRD2CKS1BSKP1 | |
| SCHEMBL29960262 | 0.77 | GAA (0.44) | ACACBACACADRD2CKS1BSKP1 | |
| SCHEMBL30031343 | 0.71 | ACACB (0.45) | ACACBACACADRD2CKS1BSKP1 | |
| SCHEMBL29960814 | 0.71 | ACACB (0.39) | ACACBACACADRD2CKS1BSKP1 | |
| SCHEMBL6483138 | 0.69 | MTNR1A (0.51) | DRD2NQO2MTNR1AMTNR1B | |
| SCHEMBL12644515 | 0.69 | TAAR1 (0.59) | DRD2 | |
| SCHEMBL29959709 | 0.69 | ACACB (0.36) | ACACBACACADRD2EPHX1 | |
| SCHEMBL29960238 | 0.68 | DRD2 (0.39) | ACACBACACADRD2CKS1BSKP1 | |
| SCHEMBL29960245 | 0.68 | BRD4 (0.41) | ACACBDRD2SPRNEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |