Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 5/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29960546 | 0.85 | ALDH1A1 (0.49) | KDM4EGAAMAPTL3MBTL1METAP1 | |
| SCHEMBL8524142 | 0.83 | CRBN (0.46) | CRBNDDB1MAPTNPC1MAPK13 | |
| SCHEMBL29960387 | 0.80 | CRBN (0.47) | CRBNDDB1MAPTNPC1MAPK13 | |
| Hydrochloric Acid SCHEMBL29960573 | 0.79 | CRBN (0.46) | CRBNDDB1MAPTNPC1MAPK13 | |
| Hydrochloric Acid SCHEMBL29960240 | 0.78 | CRBN (0.42) | CRBNDDB1ADRA2AADRA2BADRA2C | |
| SCHEMBL29960386 | 0.77 | CRBN (0.43) | CRBNDDB1MAPTNPC1MAPK13 | |
| SCHEMBL5025547 | 0.77 | ALDH1A1 (0.50) | CRBNDDB1L3MBTL1NPC1MAPK13 | |
| SCHEMBL29960465 | 0.76 | CRBN (0.40) | CRBNDDB1MAPTNPC1MAPK13 | |
| SCHEMBL1347194 | 0.74 | DDB1 (0.49) | CRBNDDB1MAPTNPC1MAPK13 | |
| SCHEMBL6441308 | 0.72 | CRBN (0.44) | CRBNDDB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |