Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6443098 | 1.00 | CRBN (0.44) | CRBNDDB1ALDH1A1IDO1EGFR | |
| SCHEMBL6439598 | 0.84 | CRBN (0.43) | CRBNDDB1 | |
| SCHEMBL29960713 | 0.82 | IDO1 (0.46) | CRBNDDB1ALDH1A1IDO1LMNA | |
| SCHEMBL5025547 | 0.80 | ALDH1A1 (0.50) | CRBNDDB1ALDH1A1EGFRLMNA | |
| SCHEMBL19984920 | 0.79 | MTNR1A (0.47) | — | |
| SCHEMBL6441669 | 0.79 | MAPK1 (0.40) | IDO1EGFRCACNA1G | |
| SCHEMBL19585657 | 0.79 | CRBN (0.64) | CRBNDDB1 | |
| SCHEMBL8524142 | 0.76 | CRBN (0.46) | CRBNDDB1ALDH1A1 | |
| SCHEMBL5279457 | 0.76 | IDO1 (0.59) | ALDH1A1IDO1EGFR | |
| SCHEMBL29960414 | 0.73 | IDO1 (0.48) | ALDH1A1IDO1LMNACACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286673-B8 | LIGANDS OF INTEGRIN RECEPTORS | ABBOTT GMBH & CO KG (DE) | 2005-07-20 | — | — | EP | disclosed |
| EP-1286673-A2 | LIGANDS OF INTEGRIN RECEPTORS | Basf Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001093840-A2 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2001-12-13 | — | — | WO | disclosed |