Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.46 |
| ▸ | BRD4 | O60885 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29960713 | 0.90 | IDO1 (0.46) | IDO1LMNACREBBPBRD4ALDH1A1 | |
| SCHEMBL15492984 | 0.85 | BRD4 (0.44) | CREBBPBRD4EPHX2DRD2PARP1 | |
| SCHEMBL30861599 | 0.85 | BRD4 (0.44) | CREBBPBRD4EPHX2DRD2PARP1 | |
| SCHEMBL29960426 | 0.79 | IDO1 (0.52) | IDO1CREBBPBRD4MAPK10EPHX2 | |
| SCHEMBL29960245 | 0.79 | BRD4 (0.41) | LMNACREBBPBRD4ALDH1A1MAPK10 | |
| SCHEMBL15492986 | 0.77 | BRD4 (0.39) | CREBBPBRD4DRD2ACACB | |
| Hydrochloric Acid SCHEMBL29959803 | 0.76 | ALDH1A1 (0.48) | IDO1LMNACREBBPBRD4ALDH1A1 | |
| SCHEMBL19980338 | 0.74 | RIPK1 (0.43) | IDO1ALDH1A1MAPK10EPHX2PARP1 | |
| SCHEMBL22343433 | 0.74 | MAOB (0.51) | CREBBPBRD4DRD2 | |
| SCHEMBL29062879 | 0.73 | LMNA (0.58) | LMNACREBBPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |