Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 4/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29960595 | 0.79 | ALDH1A1 (0.38) | ALDH1A1MAPTKDM4ECYP2C19LMNA | |
| SCHEMBL29960831 | 0.73 | ALDH1A1 (0.36) | ALDH1A1MAPTKDM4ECYP2C19LMNA | |
| SCHEMBL11444834 | 0.64 | KCNA3 (0.36) | ALDH1A1KDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL7022043 | 0.62 | LMNA (0.47) | ALDH1A1MAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL27165029 | 0.62 | NPSR1 (0.52) | ALDH1A1MAPTKDM4ECYP2C19LMNA | |
| SCHEMBL27165133 | 0.62 | NPSR1 (0.52) | ALDH1A1MAPTKDM4ECYP2C19LMNA | |
| SCHEMBL8045579 | 0.61 | NPSR1 (0.55) | ALDH1A1MAPTCYP2C19LMNANPSR1 | |
| SCHEMBL8049606 | 0.61 | NPSR1 (0.55) | ALDH1A1MAPTCYP2C19LMNANPSR1 | |
| SCHEMBL8045583 | 0.61 | NPSR1 (0.55) | ALDH1A1MAPTCYP2C19LMNANPSR1 | |
| SCHEMBL13703398 | 0.61 | CNR1 (0.46) | ALDH1A1MAPTCYP2C19CNR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |