SCHEMBL29960595

SCHEMBL29960595

CCOC(=O)CC(C[N+](=O)[O-])c1occc1OC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 12/20 0.38
CYP2C19 P33261 2/20 0.38
MAPT P10636 6/20 0.38
KDM4E B2RXH2 5/20 0.38
LMNA P02545 5/20 0.37
HPGD P15428 4/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
VCP P55072 1/20 0.35
NPSR1 Q6W5P4 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
NTSR1 P30989 1/20 0.33
POLB P06746 1/20 0.33
TNF P01375 1/20 0.33
NPC1 O15118 1/20 0.33
S1PR4 O95977 1/20 0.33
ITGA4 P13612 1/20 0.33
S1PR1 P21453 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29960449 0.79 ALDH1A1 (0.41) ALDH1A1CYP2C19MAPTKDM4ELMNA
SCHEMBL29219309 0.77 ALDH1A1 (0.39) ALDH1A1CYP2C19MAPTKDM4ELMNA
SCHEMBL29960352 0.76 ALDH1A1 (0.38) ALDH1A1CYP2C19MAPTKDM4ELMNA
SCHEMBL1269160 0.75 ALOX15 (0.46) ALDH1A1CYP2C19MAPTKDM4ELMNA
SCHEMBL6556296 0.75 ALDH1A1 (0.44) ALDH1A1CYP2C19MAPTKDM4ELMNA
SCHEMBL482069 0.74 MAPT (0.46) ALDH1A1CYP2C19MAPTKDM4ELMNA
SCHEMBL9316711 0.73 MAPT (0.34) ALDH1A1MAPTKDM4ELMNAHPGD
SCHEMBL9294262 0.73 F2 (0.50) ALDH1A1MAPTKDM4ELMNACYP3A4
SCHEMBL4809773 0.73 ALDH1A1 (0.50) ALDH1A1CYP2C19MAPTKDM4ELMNA
SCHEMBL9315762 0.73 MAPT (0.35) ALDH1A1MAPTKDM4ELMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022204150-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS BLUE OAK PHARMACEUTICALS, INC. (US) 2022-09-29 WO disclosed