SCHEMBL29960732

SCHEMBL29960732

CCOC(=O)C1OCCc2cc(Cl)cc(CCC(=O)O)c21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR17 Q13304 2/20 0.37
NPSR1 Q6W5P4 1/20 0.35
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
RXRG P48443 1/20 0.34
FFAR4 Q5NUL3 5/20 0.33
PLAU P00749 1/20 0.33
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
RECQL P46063 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
KMO O15229 1/20 0.31
CYP4F2 P78329 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29960232 0.87 TSHR (0.32) TSHRMAPK1RECQLMEN1KMT2A
SCHEMBL29960381 0.86 ALDH1A1 (0.32) TSHRMAPK1RECQLMEN1KMT2A
SCHEMBL29960448 0.80 MAOB (0.39) NPSR1TSHRMEN1KMT2AKDM4E
SCHEMBL29960462 0.73 TP53 (0.40) TSHRMAPK1MEN1KMT2AKDM4E
SCHEMBL29960986 0.71 LMNA (0.39) MEN1KMT2AKDM4EALDH1A1GAA
SCHEMBL24543296 0.68 KDM4E (0.39) TSHRMEN1KMT2AKDM4EALDH1A1
SCHEMBL27592272 0.67 RAB9A (0.38) TSHRMEN1KMT2AKDM4EALDH1A1
SCHEMBL21688271 0.66 RAB9A (0.52) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL2200994 0.65 ALDH1A1 (0.38) TSHRMEN1KMT2AKDM4EALDH1A1
SCHEMBL15919083 0.65 RAB9A (0.43) TSHRMAPK1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022204150-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS BLUE OAK PHARMACEUTICALS, INC. (US) 2022-09-29 WO disclosed