Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5013214 | 1.00 | LMNA (0.46) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL1835877 | 1.00 | LMNA (0.46) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL2996166 | 0.85 | LMNA (0.48) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL25588104 | 0.84 | LMNA (0.44) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL19859189 | 0.83 | CA12 (0.46) | GRM4CA12CA1CA2CA9 | |
| SCHEMBL13896753 | 0.83 | MEN1 (0.43) | LMNAMEN1KMT2APTGS1 | |
| Hydrochloric Acid SCHEMBL19859289 | 0.82 | CA12 (0.44) | GRM4CA12CA1CA2CA9 | |
| SCHEMBL25588108 | 0.81 | LMNA (0.42) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL28558589 | 0.80 | CA12 (0.47) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL21914796 | 0.80 | CA12 (0.47) | LMNATSHRMEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894311-B | Preparation of ethyl (2S, 3R) -2-amino-3-hydroxy-3- (4- (methylsulfonyl) phenyl) propionate | 天津工微生物科技有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-115894311-A | Preparation of ethyl (2R, 3S) -2-amino-3-hydroxy-3- (4- (methylsulfonyl) phenyl) propionate | 天津工微生物科技有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115073333-A | Racemization method based on active copper molecular sieve | 江苏八巨药业有限公司 | 2022-09-20 | — | — | CN | disclosed |
| EP-2155702-A1 | A PROCESS FOR PREPARING OXAZOLINE-PROTECTED AMINODIOL COMPOUNDS USEFUL AS INTERMEDIATES TO FLORFENICOL | Schering-Plough Ltd. (CH) | 2010-02-24 | — | — | EP | disclosed |
| US-20080319200-A1 | PROCESS FOR PREPARING OXAZOLINE-PROTECTED AMINODIOL COMPOUNDS USEFUL AS INTERMEDIATES TO FLORFENICOL | SCHERING-PLOUGH ANIMAL HEALTH CORP. | 2008-12-25 | — | — | US | disclosed |
| WO-2008150406-A1 | A PROCESS FOR PREPARING OXAZOLINE-PROTECTED AMINODIOL COMPOUNDS USEFUL AS INTERMEDIATES TO FLORFENICOL | SCHERING-PLOUGH LTD. (CH) | 2008-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319200-A1 | PROCESS FOR PREPARING OXAZOLINE-PROTECTED AMINODIOL COMPOUNDS USEFUL AS INTERMEDIATES TO FLORFENICOL | PFAS, DHFR, DDC | LMNA 1663/4885TSHR 4348/4885MEN1 1466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.