Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29965289 | 0.76 | F10 (0.47) | KIF11ALDH1A1F10NPC1RAB9A | |
| SCHEMBL19652449 | 0.72 | KIF11 (0.58) | KIF11KMT2AMEN1LMNA | |
| SCHEMBL29964989 | 0.72 | KIF11 (0.50) | KIF11ALDH1A1CRHBPCRHR2F10 | |
| SCHEMBL14356107 | 0.71 | KIF11 (0.49) | KIF11ALDH1A1F10NPC1RAB9A | |
| SCHEMBL30610089 | 0.71 | KIF11 (0.49) | KIF11ALDH1A1F10NPC1RAB9A | |
| SCHEMBL18053873 | 0.70 | KIF11 (0.52) | KIF11ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL16590556 | 0.70 | CA4 (0.46) | KIF11ALDH1A1F10NPC1RAB9A | |
| SCHEMBL15360307 | 0.70 | CA4 (0.50) | KIF11ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL17542012 | 0.69 | KIF11 (0.48) | KIF11ALDH1A1CRHBPCRHR2F10 | |
| SCHEMBL17542010 | 0.69 | KIF11 (0.48) | KIF11ALDH1A1CRHBPCRHR2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4092038-A1 | OPIOID AGONIST PEPTIDES AND USES THEREOF | Protagonist Therapeutics, Inc. (US) | 2022-11-23 | — | — | EP | disclosed |