Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 4/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14613187 | 0.87 | HDAC3 (0.47) | MAPTALDH1A1ALOX15MAPK1RECQL | |
| SCHEMBL16590556 | 0.82 | CA4 (0.46) | F10NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL6045338 | 0.76 | KCNN4 (0.55) | F10NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL10292685 | 0.76 | CA4 (0.48) | NPC1RAB9AALDH1A1LMNAKIF11 | |
| SCHEMBL14356107 | 0.76 | KIF11 (0.49) | F10NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL30610089 | 0.76 | KIF11 (0.49) | F10NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL29964161 | 0.76 | KIF11 (0.44) | F10NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL28885054 | 0.75 | GAA (0.48) | F10NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL2793473 | 0.75 | CYP2C9 (0.58) | F10NPC1RAB9AALDH1A1KIF11 | |
| SCHEMBL13539766 | 0.74 | KCNN4 (0.68) | NPC1RAB9ALMNAKIF11CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4092038-A1 | OPIOID AGONIST PEPTIDES AND USES THEREOF | Protagonist Therapeutics, Inc. (US) | 2022-11-23 | — | — | EP | disclosed |