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SCHEMBL29964906

SCHEMBL29964906

CC(C)(C)OC(=O)N1C[C@@H]2CC[C@@H](Nc3ccc(Cl)nn3)[C@@H]2C1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ USP30 Q70CQ3 5/20 0.44
▸ SSTR4 P31391 1/20 0.39
▸ ALDH1A1 P00352 2/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ MAPK1 P28482 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ NR1H2 P55055 1/20 0.37
▸ KMT2A Q03164 2/20 0.36
▸ LMNA P02545 1/20 0.36
▸ POLB P06746 1/20 0.36
▸ STS P08842 3/20 0.36
▸ JAK1 P23458 1/20 0.36
▸ DDB1 Q16531 1/20 0.36
▸ CRBN Q96SW2 1/20 0.36
▸ GPR119 Q8TDV5 1/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ PDE4B Q07343 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30762021 1.00 USP30 (0.44) USP30SSTR4ALDH1A1NPC1MAPT
SCHEMBL22398078 1.00 USP30 (0.44) USP30SSTR4ALDH1A1NPC1MAPT
SCHEMBL22600419 0.88 USP30 (0.44) USP30SSTR4ALDH1A1NPC1MAPT
SCHEMBL30762023 0.88 USP30 (0.44) USP30SSTR4ALDH1A1NPC1MAPT
SCHEMBL29964673 0.88 USP30 (0.44) USP30SSTR4ALDH1A1NPC1MAPT
SCHEMBL25507146 0.85 USP30 (0.39) USP30SSTR4ALDH1A1NPC1MAPT
SCHEMBL25508024 0.85 USP30 (0.39) USP30SSTR4ALDH1A1NPC1MAPT
SCHEMBL22702770 0.85 SSTR4 (0.41) USP30SSTR4ALDH1A1NPC1MAPT
SCHEMBL29864697 0.85 SSTR4 (0.41) USP30SSTR4ALDH1A1NPC1MAPT
SCHEMBL22398023 0.83 LMNA (0.35) ALDH1A1MAPTHTTKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600730-B2 Substituted cyclopenta[c]pyrroles as ABHD6 antagonists ONO PHARMACEUTICAL CO., LTD. (JP) 2026-04-14 — — US disclosed
US-20240270755-A1 SUBSTITUTED CYCLOPENTA[c]PYRROLES AS ABHD6 ANTAGONISTS ONO PHARMACEUTICAL CO., LTD. (JP) 2024-08-15 — — US disclosed
EP-4317153-A1 ABHD6 ANTAGONIST ONO Pharmaceutical Co., Ltd. (JP) 2024-02-07 — — EP disclosed
US-20240010658-A1 ABHD6 ANTAGONIST ONO PHARMACEUTICAL CO., LTD. (JP) 2024-01-11 — — US disclosed
WO-2022211060-A1 ABHD6 ANTAGONIST 小野薬品工業株式会社 2022-10-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240010658-A1 ABHD6 ANTAGONIST ABHD6, ABHD16A, ABHD12 USP30 208/4885SSTR4 4276/4885ALDH1A1 994/4885
US-20240270755-A1 SUBSTITUTED CYCLOPENTA[c]PYRROLES AS ABHD6 ANTAGONISTS ABHD6, ABHD16A, PITHD1 USP30 269/4885SSTR4 4034/4885ALDH1A1 1199/4885
US-12600730-B2 Substituted cyclopenta[c]pyrroles as ABHD6 antagonists ABHD6, ABHD16A, HDHD5 USP30 498/4885SSTR4 3293/4885ALDH1A1 548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.