Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.60 |
| ▸ | STAT3 | P40763 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.52 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.52 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.52 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.52 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | TPH1 | P17752 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29378321 | 1.00 | LDHA (0.60) | LDHASTAT3KDM4EATMGRIK1 | |
| SCHEMBL27484664 | 0.87 | GRIK1 (0.49) | LDHASTAT3ATMGRIK1GRIA1 | |
| SCHEMBL5345575 | 0.87 | GRIK1 (0.49) | LDHASTAT3KDM4EGRIK1GRIA1 | |
| SCHEMBL5345580 | 0.87 | GRIK1 (0.49) | LDHASTAT3KDM4EGRIK1GRIA1 | |
| SCHEMBL27484663 | 0.87 | GRIK1 (0.49) | LDHASTAT3ATMGRIK1GRIA1 | |
| SCHEMBL27503386 | 0.87 | GRIK1 (0.49) | LDHASTAT3ATMGRIK1GRIA1 | |
| SCHEMBL22445062 | 0.87 | STAT3 (0.57) | LDHASTAT3KDM4EATMCYP19A1 | |
| SCHEMBL20683363 | 0.85 | CYP3A4 (0.65) | LDHAKDM4EKMT2AALDH1A1AOC3 | |
| SCHEMBL10452371 | 0.85 | ALOX5 (0.52) | LDHASTAT3KDM4EATMKMT2A | |
| SCHEMBL159001 | 0.84 | LDHA (0.73) | LDHAKDM4ETPH1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4092038-A1 | OPIOID AGONIST PEPTIDES AND USES THEREOF | Protagonist Therapeutics, Inc. (US) | 2022-11-23 | — | — | EP | disclosed |