Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 8/20 | 0.51 |
| ▸ | METTL14 | Q9HCE5 | 8/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.45 |
| ▸ | DRD1 | P21728 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23481976 | 1.00 | METTL3 (0.51) | METTL3METTL14HRH3DRD1DRD3 | |
| SCHEMBL23481977 | 0.83 | HRH3 (0.62) | METTL3METTL14HRH3SIGMAR1CHRNA7 | |
| SCHEMBL23482004 | 0.79 | DRD3 (0.48) | METTL3METTL14HRH3DRD1DRD3 | |
| SCHEMBL31519271 | 0.71 | DRD3 (0.46) | METTL3METTL14DRD1DRD3TMEM97 | |
| SCHEMBL29919205 | 0.71 | METTL3 (0.50) | METTL3METTL14DRD1DRD3TMEM97 | |
| SCHEMBL23458922 | 0.71 | METTL3 (0.50) | METTL3METTL14DRD1DRD3TMEM97 | |
| Lithium SCHEMBL29919186 | 0.70 | METTL3 (0.49) | METTL3METTL14DRD1DRD3TMEM97 | |
| SCHEMBL23482013 | 0.69 | LOXL2 (0.46) | LOXL2GAAPKM | |
| SCHEMBL27792587 | 0.66 | GAA (0.39) | LOXL2GAAPKM | |
| SCHEMBL25976935 | 0.63 | METTL3 (0.55) | METTL3METTL14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151540-A | Polyheterocyclic compounds as METTL3 inhibitors | 风暴治疗有限公司 | 2022-10-04 | — | — | CN | disclosed |