Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 10/20 | 0.71 |
| ▸ | MAPT | P10636 | 8/20 | 0.71 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.49 |
| ▸ | NPC1 | O15118 | 8/20 | 0.47 |
| ▸ | RAB9A | P51151 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MITF | O75030 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5300838 | 0.83 | TP53 (0.62) | TP53MAPTGAAF2RL3SMN1; SMN2 | |
| SCHEMBL11146043 | 0.83 | TP53 (0.71) | TP53MAPTGAAF2RL3SMN1; SMN2 | |
| SCHEMBL19475525 | 0.72 | F2RL3 (0.67) | TP53MAPTGAAF2RL3SMN1; SMN2 | |
| SCHEMBL19510035 | 0.71 | F2RL3 (0.65) | TP53MAPTGAAF2RL3SMN1; SMN2 | |
| SCHEMBL25270121 | 0.70 | HPGD (0.59) | TP53MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL12692485 | 0.70 | SMN1; SMN2 (0.70) | TP53MAPTGAASMN1; SMN2NPC1 | |
| SCHEMBL19509939 | 0.69 | F2RL3 (1.00) | TP53MAPTF2RL3SMN1; SMN2 | |
| Bromide SCHEMBL3869607 | 0.69 | SMN1; SMN2 (0.68) | TP53MAPTGAASMN1; SMN2NPC1 | |
| SCHEMBL12997562 | 0.68 | SMN1; SMN2 (0.57) | TP53MAPTGAAF2RL3SMN1; SMN2 | |
| SCHEMBL17750392 | 0.67 | RAB9A (0.60) | TP53MAPTGAAF2RL3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197813-A1 | Heterocyclic Compounds as Sweetener Enhancers | REDPOINT BIO CORPORATION (US) | 2010-08-05 | — | — | US | claimed |
| US-7674831-B2 | Heterocyclic compounds as sweetener enhancers | REDPOINT BIO CORPORATION (US) | 2010-03-09 | — | — | US | claimed |
| US-20080249189-A1 | HETEROCYCLIC COMPOUNDS AS SWEETENER ENHANCERS | REDPOINT BIO CORPORATION | 2008-10-09 | — | — | US | claimed |
| US-20100197813-A1 | Heterocyclic Compounds as Sweetener Enhancers | REDPOINT BIO CORPORATION (US) | 2010-08-05 | — | — | US | disclosed |
| US-20100197813-A1 | Heterocyclic Compounds as Sweetener Enhancers | REDPOINT BIO CORPORATION (US) | 2010-08-05 | — | — | US | disclosed |
| US-20100197813-A1 | Heterocyclic Compounds as Sweetener Enhancers | REDPOINT BIO CORPORATION (US) | 2010-08-05 | — | — | US | disclosed |
| US-7674831-B2 | Heterocyclic compounds as sweetener enhancers | REDPOINT BIO CORPORATION (US) | 2010-03-09 | — | — | US | disclosed |
| US-7674831-B2 | Heterocyclic compounds as sweetener enhancers | REDPOINT BIO CORPORATION (US) | 2010-03-09 | — | — | US | disclosed |
| US-7674831-B2 | Heterocyclic compounds as sweetener enhancers | REDPOINT BIO CORPORATION (US) | 2010-03-09 | — | — | US | disclosed |
| US-20080249189-A1 | HETEROCYCLIC COMPOUNDS AS SWEETENER ENHANCERS | REDPOINT BIO CORPORATION | 2008-10-09 | — | — | US | disclosed |
| US-20080249189-A1 | HETEROCYCLIC COMPOUNDS AS SWEETENER ENHANCERS | REDPOINT BIO CORPORATION | 2008-10-09 | — | — | US | disclosed |
| US-20080249189-A1 | HETEROCYCLIC COMPOUNDS AS SWEETENER ENHANCERS | REDPOINT BIO CORPORATION | 2008-10-09 | — | — | US | disclosed |
| WO-2008024364-A2 | HETEROCYCLIC COMPOUNDS AS SWEETENER ENHANCERS | REDPOINT BIO CORPORATION (US) | 2008-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249189-A1 | HETEROCYCLIC COMPOUNDS AS SWEETENER ENHANCERS | TAS2R1, TAS1R1, TAS2R40 | TP53 1811/4885MAPT 4423/4885GAA 935/4885 |
| US-20100197813-A1 | Heterocyclic Compounds as Sweetener Enhancers | TAS2R1, TAS1R1, TAS2R40 | TP53 1811/4885MAPT 4423/4885GAA 935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.