Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | HTT | P42858 | 2/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24554275 | 1.00 | KDM4E (0.77) | KDM4ESMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL28596558 | 0.84 | KDM4E (0.70) | KDM4ESMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL9942079 | 0.84 | KDM4E (0.68) | KDM4ESMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL5466948 | 0.81 | ACLY (0.56) | KDM4ESMN1; SMN2LMNAHTTPOLB | |
| SCHEMBL38662886 | 0.80 | POLB (0.65) | KDM4ESMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL13633521 | 0.79 | CA12 (0.52) | KDM4ESMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL16897001 | 0.78 | HSD11B1 (0.60) | KDM4ESMN1; SMN2LMNAHTTPOLB | |
| SCHEMBL12460797 | 0.78 | KDM4E (0.59) | KDM4ESMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL1667129 | 0.78 | KDM4E (0.75) | KDM4ESMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL3434693 | 0.77 | KDM4E (0.58) | KDM4ESMN1; SMN2LMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115124459-A | Method for selectively nitrating N- (2-pyridyl) benzene sulfonamide compound | 宁波大学 | 2022-09-30 | — | — | CN | disclosed |