SCHEMBL3434693

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2177837	0.84	CYP2C19 (0.68)	KDM4EALDH1A1TSHRNPSR1SMN1; SMN2
	SCHEMBL2180044	0.81	KMT2A (0.55)	KDM4EALDH1A1SMN1; SMN2LMNACYP2C19
	SCHEMBL8055002	0.80	KMO (0.52)	KDM4EALDH1A1HPGDHSD17B10KMO
	SCHEMBL31633227	0.80	CYP2C19 (0.75)	KDM4EALDH1A1KMOTSHRGAA
	SCHEMBL30978874	0.79	ALDH1A1 (0.72)	KDM4EALDH1A1TSHRPKMNPSR1
	SCHEMBL24554275	0.77	KDM4E (0.77)	KDM4EALDH1A1HPGDPKMNPSR1
	SCHEMBL29967291	0.77	KDM4E (0.77)	KDM4EALDH1A1HPGDPKMNPSR1
	SCHEMBL1381858	0.77	PDE4A (0.73)	KDM4EALDH1A1HPGDHSD17B10TSHR
	SCHEMBL1094344	0.75	ALDH1A1 (0.59)	KDM4EALDH1A1HPGDHSD17B10TSHR
	SCHEMBL12900075	0.74	POLB (0.52)	KDM4EALDH1A1HPGDHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.