Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 8/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | BCR | P11274 | 2/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ASPH | Q12797 | 1/20 | 0.34 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | BRS3 | P32247 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29968332 | 0.89 | ACMSD (0.38) | MAPK8ACMSDSERPINE1AGTR2DHODH | |
| SCHEMBL29967914 | 0.89 | AGTR2 (0.40) | MAPK8ABL1BCRACMSDSERPINE1 | |
| SCHEMBL29968259 | 0.86 | AGTR2 (0.37) | MAPK8ABL1BCRACMSDAGTR2 | |
| SCHEMBL31029250 | 0.84 | DHODH (0.39) | MAPK8ABL1BCRACMSDAGTR2 | |
| SCHEMBL29967996 | 0.81 | ABL1 (0.38) | MAPK8ABL1BCR | |
| SCHEMBL29968331 | 0.80 | KDM4C (0.38) | MAPK8ACMSDSERPINE1KDM4EAGTR2 | |
| SCHEMBL29967968 | 0.77 | MAPK10 (0.44) | MAPK8SERPINE1 | |
| SCHEMBL29968241 | 0.77 | ACMSD (0.36) | MAPK8ABL1BCRACMSDSERPINE1 | |
| SCHEMBL29967707 | 0.76 | MAPK10 (0.43) | MAPK8ABL1BCRAGTR2 | |
| SCHEMBL29968299 | 0.76 | KIT (0.43) | MAPK8ABL1BCRHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260165-B | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2024-08-06 | — | — | CN | disclosed |
| CN-115260165-A | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2022-11-01 | — | — | CN | disclosed |