Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | BCR | P11274 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 6/20 | 0.36 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 4/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31029250 | 0.91 | DHODH (0.39) | AGTR2ABL1BCRKDRCLCN2 | |
| SCHEMBL29967914 | 0.90 | AGTR2 (0.40) | AGTR2ABL1BCRKDRCLCN2 | |
| SCHEMBL29967523 | 0.86 | MAPK8 (0.41) | AGTR2ABL1BCRMAPK8ACMSD | |
| SCHEMBL29968332 | 0.86 | ACMSD (0.38) | AGTR2KDRCLCN2MAPK8MAPK9 | |
| SCHEMBL29967996 | 0.82 | ABL1 (0.38) | ABL1BCRKDRMAPK8MAPK9 | |
| SCHEMBL29968331 | 0.81 | KDM4C (0.38) | AGTR2KDRMAPK8AGTR1MAPK9 | |
| SCHEMBL29968299 | 0.79 | KIT (0.43) | ABL1BCRKDRMAPK8 | |
| SCHEMBL29967968 | 0.78 | MAPK10 (0.44) | KDRMAPK8MAPK9MAPK10 | |
| SCHEMBL29968241 | 0.78 | ACMSD (0.36) | AGTR2ABL1BCRKDRMAPK8 | |
| SCHEMBL29967707 | 0.77 | MAPK10 (0.43) | AGTR2ABL1BCRKDRMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260165-B | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2024-08-06 | — | — | CN | disclosed |
| CN-115260165-A | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2022-11-01 | — | — | CN | disclosed |