Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 7/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | HK1 | P19367 | 1/20 | 0.53 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.46 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nicotyrine SCHEMBL29398389 | 1.00 | CYP2A6 (1.00) | CYP2A6ALDH1A1CYP2A13CYP1A2CYP3A4 | |
| SCHEMBL21022692 | 0.82 | CYP2A6 (0.69) | CYP2A6ALDH1A1CYP2A13CYP1A2CYP3A4 | |
| Nicotyrine SCHEMBL6845683 | 0.81 | ALDH1A1 (0.65) | CYP2A6ALDH1A1CYP2A13CYP1A2CYP3A4 | |
| Nicotine SCHEMBL11780357 | 0.79 | ALDH1A1 (0.71) | CYP2A6ALDH1A1CYP2A13CYP3A4CYP2C19 | |
| SCHEMBL2460181 | 0.78 | PPARA (0.64) | CYP2A6ALDH1A1CYP2A13HSD17B10SMN1; SMN2 | |
| SCHEMBL1133225 | 0.77 | CYP2A6 (0.62) | CYP2A6ALDH1A1CYP2A13CYP1A2CYP3A4 | |
| SCHEMBL31627317 | 0.77 | CYP2A6 (0.62) | CYP2A6ALDH1A1CYP2A13CYP1A2CYP3A4 | |
| SCHEMBL29150836 | 0.76 | ALDH1A1 (0.61) | CYP2A6ALDH1A1CYP2A13CYP1A2CYP3A4 | |
| SCHEMBL30577111 | 0.75 | CYP2A6 (0.60) | CYP2A6ALDH1A1CYP2A13CYP1A2CYP3A4 | |
| SCHEMBL6444709 | 0.74 | PCSK9 (0.73) | CYP2A6ALDH1A1CYP2A13CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117897440-A | Method for screening solvent for extraction of polyvinyl chloride, method for recycling waste material, recycled polyvinyl chloride and composition | 株式会社LG化学 | 2024-04-16 | — | — | CN | claimed |
| CN-117897439-A | Method for screening solvent for extraction of polyvinyl chloride, method for recovering waste material, and recovered polyvinyl chloride and composition | 株式会社LG化学 | 2024-04-16 | — | — | CN | claimed |
| WO-2023195790-A1 | METHOD FOR MANUFACTURING BIOMATERIAL FOR TISSUE REPAIR WITH EXCELLENT SAFETY | ㈜아크로스 | 2023-10-12 | — | — | WO | claimed |
| CN-1373169-A | Ink composition | IND TECHNOLOGY INST (CN) | 2002-10-09 | — | — | CN | claimed |
| US-20020025477-A1 | Non-aqueous electrolytic solution and secondary battery containing same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-02-28 | — | — | US | claimed |
| EP-1172878-A2 | Non-aqueous electrolytic solution and secondary battery containing same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-01-16 | — | — | EP | claimed |
| US-4065561-A | Method of inducing skeletal muscle relaxation | GASSEL MYRON MICHAEL | 1977-12-27 | — | — | US | claimed |
| US-20250009006-A1 | ORAL PRODUCT | ALTRIA CLIENT SERVICES LLC (US) | 2025-01-09 | — | — | US | disclosed |
| US-20240415827-A1 | NICOTINE LOZENGE | ALTRIA CLIENT SERVICES LLC (US) | 2024-12-19 | — | — | US | disclosed |
| US-12167743-B2 | Oral product | ALTRIA CLIENT SERVICES LLC (US) | 2024-12-17 | — | — | US | disclosed |
| US-12083110-B2 | Nicotine lozenge | ALTRIA CLIENT SERVICES LLC (US) | 2024-09-10 | — | — | US | disclosed |
| EP-4001355-B1 | ORAL PRODUCT | ALTRIA CLIENT SERVICES LLC (US) | 2024-08-07 | — | — | EP | disclosed |
| US-20240246929-A1 | PREPARATION METHOD OF L-NICOTINE | HUANGGANG ZY BIOTECHNOLOGY CO., LTD. (CN) | 2024-07-25 | — | — | US | disclosed |
| US-4065561-A | Method of inducing skeletal muscle relaxation | GASSEL MYRON MICHAEL | 1977-12-27 | — | — | US | disclosed |
| US-4065561-A | Method of inducing skeletal muscle relaxation | GASSEL MYRON MICHAEL | 1977-12-27 | — | — | US | disclosed |
| US-4018926-A | Alkyl 4-[o-(substituted methyleneamino)-phenyl]-3-thioallophanate miticides and fungicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-04-19 | — | — | US | disclosed |
| US-4011213-A | FUNGICIDES, MITE OVICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-03-08 | — | — | US | disclosed |
| US-4007258-A | Sustained release pesticidal composition | UNION CORPORATION (US) | 1977-02-08 | — | — | US | disclosed |
| US-3958007-A | FUNGICIDES, MITE OVICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-05-18 | — | — | US | disclosed |
| US-3950391-A | FUNGICIDES, MITICIDES, OVICIDES | ADAMS CHARLES D | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246929-A1 | PREPARATION METHOD OF L-NICOTINE | CHRNA5, CHRNA9, NAPRT | CYP2A6 2419/4885ALDH1A1 1351/4885CYP2A13 2430/4885 |
| US-20240415827-A1 | NICOTINE LOZENGE | MGAM, LCT, MYO1G | CYP2A6 1157/4885ALDH1A1 3390/4885CYP2A13 2332/4885 |
| US-12083110-B2 | Nicotine lozenge | MGAM, LCT, MYO1G | CYP2A6 1157/4885ALDH1A1 3390/4885CYP2A13 2332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.