Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2262766 | 0.89 | CYP3A4 (0.52) | ALDH1A1L3MBTL1MAPTSMN1; SMN2LMNA | |
| SCHEMBL4788462 | 0.88 | VEGFA (0.55) | SMN1; SMN2KDM1ATP53STSP2RX3 | |
| SCHEMBL327042 | 0.87 | TP53 (0.50) | L3MBTL1TP53STSKDM4EHDAC1 | |
| SCHEMBL5313737 | 0.86 | HDAC1 (0.61) | ALDH1A1MAPTSMN1; SMN2LMNATP53 | |
| SCHEMBL22367284 | 0.84 | GAA (0.51) | ALDH1A1L3MBTL1MAPTSMN1; SMN2LMNA | |
| SCHEMBL8294396 | 0.83 | MMP1 (0.47) | ALDH1A1L3MBTL1MAPTSMN1; SMN2LMNA | |
| SCHEMBL10039879 | 0.83 | ALDH1A1 (0.62) | ALDH1A1MAPTSMN1; SMN2LMNAKDM1A | |
| SCHEMBL23728272 | 0.80 | SMN1; SMN2 (0.52) | ALDH1A1L3MBTL1MAPTSMN1; SMN2LMNA | |
| SCHEMBL11432095 | 0.79 | GAA (0.68) | ALDH1A1L3MBTL1MAPTSMN1; SMN2GAA | |
| SCHEMBL22770534 | 0.79 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11401270-B2 | Alcoxyamino derivatives for treating pain and pain related conditions | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2022-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11401270-B2 | Alcoxyamino derivatives for treating pain and pain related conditions | CACNA1B, CACNA1G, CACNA2D2 | ALDH1A1 713/4885L3MBTL1 4623/4885MAPT 1145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.