Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29967901 | 0.91 | AGTR1 (0.56) | PPARGAGTR1AGTR2 | |
| SCHEMBL29967991 | 0.89 | PPARG (0.58) | PPARGAGTR1AGTR2 | |
| SCHEMBL29967925 | 0.89 | PPARG (0.49) | PPARGAGTR1AGTR2 | |
| SCHEMBL29968278 | 0.88 | PPARG (0.49) | PPARGAGTR1AGTR2 | |
| SCHEMBL29968417 | 0.87 | CNR2 (0.41) | PPARG | |
| SCHEMBL29968012 | 0.84 | NR1H4 (0.46) | PPARGAGTR1AGTR2 | |
| SCHEMBL29968167 | 0.82 | NR1H4 (0.44) | PPARG | |
| SCHEMBL29967498 | 0.81 | NR1H4 (0.44) | PPARG | |
| SCHEMBL29968184 | 0.81 | PPARG (0.43) | PPARG | |
| SCHEMBL29968086 | 0.80 | PPARG (0.45) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260165-B | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2024-08-06 | — | — | CN | disclosed |
| CN-115260165-A | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2022-11-01 | — | — | CN | disclosed |