Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 4/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.39 |
| ▸ | OXTR | P30559 | 2/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23319968 | 1.00 | HAO1 (0.50) | HAO1MKNK1MKNK2HSD17B1HSD17B2 | |
| SCHEMBL23319889 | 0.90 | HAO1 (0.54) | HAO1MKNK1MKNK2PRKAG1PRKAA1 | |
| SCHEMBL31166249 | 0.87 | HAO1 (0.44) | HAO1MKNK1MKNK2PRKAG1PRKAA1 | |
| SCHEMBL23319906 | 0.87 | HAO1 (0.44) | HAO1MKNK1MKNK2PRKAG1PRKAA1 | |
| SCHEMBL21296847 | 0.86 | PRKAG1 (0.51) | HAO1PRKAG1PRKAA1PRKAB1LMNA | |
| SCHEMBL23319935 | 0.85 | HAO1 (0.48) | HAO1PRKAG1PRKAA1PRKAB1EGLN1 | |
| SCHEMBL29692340 | 0.85 | HAO1 (0.70) | HAO1ACACB | |
| SCHEMBL23001778 | 0.85 | HAO1 (0.70) | HAO1ACACB | |
| SCHEMBL23319961 | 0.84 | HAO1 (0.39) | HAO1PRKAG1PRKAA1PRKAB1ALPL | |
| SCHEMBL21296956 | 0.82 | HAO1 (0.52) | HAO1PRKAG1PRKAA1PRKAB1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230143491-A1 | TRIAZOLE GLYCOLATE OXIDASE INHIBITORS | PHOENIX TISSUE REPAIR, INC. | 2023-05-11 | — | — | US | disclosed |
| US-11401246-B2 | Triazole glycolate oxidase inhibitors | Cantero Therapeutics, Inc. (US) | 2022-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11401246-B2 | Triazole glycolate oxidase inhibitors | XDH, DUOX1, PNPO | HAO1 6/4885MKNK1 2889/4885MKNK2 2553/4885 |
| US-20230143491-A1 | TRIAZOLE GLYCOLATE OXIDASE INHIBITORS | XDH, DUOX1, PNPO | HAO1 6/4885MKNK1 2889/4885MKNK2 2553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.