Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19647913 | 0.95 | GRIK1 (0.41) | GRIK1GRIK2GPR84FFAR1EPHX1 | |
| SCHEMBL7061809 | 0.81 | GPR84 (0.44) | GPR84FFAR1EPHX1MAPTLCK | |
| SCHEMBL3472515 | 0.77 | GPR84 (0.41) | GRIK1GRIK2GPR84FFAR1MAPT | |
| SCHEMBL20341607 | 0.74 | GPR84 (0.44) | GRIK1GRIK2GPR84FFAR1MAPT | |
| SCHEMBL17818503 | 0.73 | GPR84 (0.41) | GPR84FFAR1EPHX1MAPTLCK | |
| SCHEMBL4553798 | 0.72 | EPHX1 (0.39) | GRIK1GRIK2GPR84FFAR1EPHX1 | |
| SCHEMBL8972391 | 0.72 | EPHX1 (0.39) | GRIK1GRIK2GPR84FFAR1EPHX1 | |
| Hydrochloric Acid SCHEMBL10586223 | 0.71 | OPRM1 (0.37) | GRIK1GRIK2MAPTLAP3 | |
| SCHEMBL14576719 | 0.69 | CA2 (0.36) | GPR84FFAR1SLC1A2SLC1A1CA2 | |
| SCHEMBL17099453 | 0.68 | GPR84 (0.50) | GPR84FFAR1MAPTLCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151534-A | Inhibitors of interleukin-1 receptor-related kinase (IRAK)/FMS-like receptor tyrosine kinase (FLT 3), pharmaceutical products thereof, and methods thereof | 南京药石科技股份有限公司 | 2022-10-04 | — | — | CN | disclosed |