Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | ACE | P12821 | 6/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272757 | 0.83 | ACE (0.43) | DPP4DPP8DPP9DPP7F2 | |
| SCHEMBL11037632 | 0.83 | ACE (0.43) | DPP4DPP8DPP9DPP7F2 | |
| SCHEMBL10901745 | 0.81 | OPRM1 (0.51) | F2 | |
| Hydrochloric Acid SCHEMBL10657494 | 0.81 | DPP8 (0.54) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL31099289 | 0.81 | NRP1 (0.51) | F2 | |
| Sulfuric Acid SCHEMBL9733221 | 0.80 | DPP4 (0.45) | DPP4DPP8DPP9DPP7F2 | |
| SCHEMBL8072324 | 0.80 | BDKRB2 (0.58) | F2 | |
| Sulfuric Acid SCHEMBL28295501 | 0.80 | ACE (0.40) | DPP4DPP8DPP9DPP7F2 | |
| Sulfuric Acid SCHEMBL28295504 | 0.80 | ACE (0.40) | DPP4DPP8DPP9DPP7F2 | |
| SCHEMBL48888 | 0.79 | TMPRSS11D (0.44) | DPP4DPP8DPP9DPP7F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8258273-B1 | Isolated genomic polynucleotide fragments from chromosome 10q25.3 that encode human soluble aminopeptidase P | RYOGEN LLC | 2012-09-04 | — | — | US | disclosed |
| US-7786280-B1 | Isolated genomic polynucleotide fragments from chromosome 10q25.3 that encode human soluble aminopeptidase P | RYOGEN LLC (US) | 2010-08-31 | — | — | US | disclosed |
| US-7273718-B1 | Isolated genomic polynucleotide fragments from chromosome 10q25.3 that encode human soluble aminopeptidase P | RYOGEN LLC (US) | 2007-09-25 | — | — | US | disclosed |