Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | PRNP | P04156 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26352907 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2MAPTRAB9ANOS3NOS1 | |
| SCHEMBL22369571 | 0.80 | NOS3 (0.50) | SMN1; SMN2MAPTRAB9ANOS3NOS1 | |
| SCHEMBL26353179 | 0.78 | CHRNB2 (0.36) | CHRNB2CHRNA4 | |
| SCHEMBL29973118 | 0.78 | CHRNB2 (0.36) | CHRNB2CHRNA4 | |
| SCHEMBL20951048 | 0.77 | ALDH1A1 (0.36) | SMN1; SMN2KDM4E | |
| SCHEMBL29383919 | 0.76 | NOS3 (0.56) | SMN1; SMN2MAPTRAB9ANOS3NOS1 | |
| SCHEMBL425866 | 0.76 | NOS3 (0.56) | SMN1; SMN2MAPTRAB9ANOS3NOS1 | |
| SCHEMBL23591573 | 0.75 | CYP1A2 (0.47) | SMN1; SMN2MAPTRAB9ANOS3NOS1 | |
| SCHEMBL20687400 | 0.74 | NOS3 (0.54) | SMN1; SMN2MAPTRAB9ANOS3NOS1 | |
| SCHEMBL29972541 | 0.72 | ACHE (0.31) | PRNPRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114845778-A | Dihydrocyclopentaisoquinoline sulfonamide derivative compound | UCB生物制药有限责任公司 | 2022-08-02 | — | — | CN | disclosed |