Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.55 |
| ▸ | APLNR | P35414 | 2/20 | 0.55 |
| ▸ | CALCR | P30988 | 3/20 | 0.53 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 3/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.50 |
| ▸ | CTSK | P43235 | 3/20 | 0.50 |
| ▸ | CTSH | P09668 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | REN | P00797 | 1/20 | 0.48 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29695502 | 0.87 | APLNR (0.64) | F2APLNRCALCRMC4RCTSL | |
| SCHEMBL30627978 | 0.86 | REN (0.64) | REN | |
| SCHEMBL31119149 | 0.86 | F2 (0.52) | F2APLNRCALCRRENCXCL8 | |
| SCHEMBL30512591 | 0.86 | APLNR (0.54) | F2APLNRCALCRCRHR1CRHR2 | |
| SCHEMBL29941484 | 0.85 | F2 (0.58) | F2APLNRCALCRCRHR1CRHR2 | |
| SCHEMBL29972926 | 0.85 | CCKAR (0.49) | CALCR | |
| SCHEMBL31607154 | 0.84 | AGTR2 (0.54) | F2CALCROPRD1REN | |
| SCHEMBL31437675 | 0.84 | REN (0.53) | F2CALCRREN | |
| SCHEMBL31206334 | 0.84 | APLNR (0.59) | F2APLNRCALCROPRM1OPRD1 | |
| SCHEMBL30456911 | 0.83 | APLNR (0.52) | APLNRCTSLCTSSCTSKCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4067370-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF PEPTIDES AND PEPTIDE RELATED COMPOUNDS | Yu, Chongxi (US) | 2022-10-05 | — | — | EP | disclosed |