SCHEMBL30512591

CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)CNC(=O)[C@@H](N)CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	APLNR	P35414	3/20	0.54

▸	F2	P00734	4/20	0.52

▸	CALCR	P30988	3/20	0.51

▸	CRHR1	P34998	1/20	0.49

▸	CRHR2	Q13324	1/20	0.49

▸	CTSL	P07711	2/20	0.48

▸	CTSS	P25774	2/20	0.48

▸	CTSK	P43235	2/20	0.48

▸	CTSH	P09668	1/20	0.47

▸	GLP1R	P43220	3/20	0.47

▸	GCGR	P47871	3/20	0.47

▸	RAMP1	O60894	1/20	0.46

▸	CALCRL	Q16602	1/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29972919	0.86	F2 (0.55)	APLNRF2CALCRCRHR1CRHR2
SCHEMBL31195334	0.86	CALCRL (0.53)	APLNRF2RAMP1CALCRL
SCHEMBL31119149	0.84	F2 (0.52)	APLNRF2CALCR
SCHEMBL29941484	0.83	F2 (0.58)	APLNRF2CALCRCRHR1CRHR2
SCHEMBL31206334	0.82	APLNR (0.59)	APLNRF2CALCR
SCHEMBL29736701	0.81	APLNR (0.56)	APLNRF2CALCRCRHR1CRHR2
SCHEMBL7200318	0.81	CTSL (0.49)	APLNRF2CALCRCTSLCTSS
SCHEMBL7200319	0.81	CTSL (0.49)	APLNRF2CALCRCTSLCTSS
SCHEMBL30456911	0.81	APLNR (0.52)	APLNRCTSLCTSSCTSKCTSH
SCHEMBL29521043	0.80	F2 (0.54)	APLNRF2CALCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-116490215-A	Targeted mediated endocytic drug delivery	CRM医疗有限公司	2023-07-25	—	—	CN	disclosed