Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924698 | 0.82 | ALDH1A1 (0.54) | PTGS2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL1457013 | 0.81 | ALDH1A1 (0.50) | PTGS2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL2785910 | 0.78 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1TDP1POLB | |
| SCHEMBL10452127 | 0.78 | PTGS2 (0.43) | PTGS2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL10684532 | 0.78 | RAB9A (0.58) | PTGS2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL6573092 | 0.78 | PTGS2 (0.55) | PTGS2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL11594461 | 0.77 | PTGS2 (0.48) | PTGS2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL5935200 | 0.76 | PTGS2 (0.56) | PTGS2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL8889748 | 0.74 | TDP1 (0.51) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL28225493 | 0.74 | RAB9A (0.47) | PTGS2RAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081199-A2 | LIPOXYGENASE INHIBITORS | SRI International (US) | 2022-11-02 | — | — | EP | disclosed |