SCHEMBL29973046

CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	KISS1R	Q969F8	15/20	0.62

▸	IL23R	Q5VWK5	1/20	0.57

▸	GLP1R	P43220	2/20	0.56

▸	OPRM1	P35372	2/20	0.56

▸	OPRD1	P41143	2/20	0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Wtlnsagyll SCHEMBL29682704	0.93	OPRM1 (0.64)	KISS1ROPRM1OPRD1
SCHEMBL30622601	0.91	KISS1R (0.58)	KISS1RIL23R
SCHEMBL31232499	0.91	GLP1R (0.68)	KISS1RGLP1R
SCHEMBL30906555	0.90	GLP1R (0.68)	KISS1RIL23RGLP1R
SCHEMBL30973913	0.90	NPBWR1 (0.65)	KISS1ROPRM1OPRD1
SCHEMBL30906506	0.90	GLP1R (0.68)	KISS1RIL23RGLP1R
SCHEMBL30906510	0.89	GLP1R (0.67)	KISS1RIL23RGLP1R
SCHEMBL30429448	0.88	GALR2 (0.62)	KISS1RGLP1R
SCHEMBL30906532	0.88	GLP1R (0.71)	KISS1RIL23RGLP1R
SCHEMBL31683311	0.88	GLP1R (0.67)	IL23RGLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4067370-A1	HIGH PENETRATION PRODRUG COMPOSITIONS OF PEPTIDES AND PEPTIDE RELATED COMPOUNDS	Yu, Chongxi (US)	2022-10-05	—	—	EP	disclosed