Wtlnsagyll

Wtlnsagyll

SCHEMBL29682704

CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)[C@@H](C)O)C(=O)O

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 2/20 0.64
▸ OPRD1 P41143 2/20 0.64
▸ NPBWR1 P48145 4/20 0.62
▸ KISS1R Q969F8 14/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30973913 0.96 NPBWR1 (0.65) OPRM1OPRD1NPBWR1KISS1R
SCHEMBL29973046 0.93 KISS1R (0.62) OPRM1OPRD1KISS1R
SCHEMBL29425581 0.89 KISS1R (0.59) OPRM1OPRD1KISS1R
SCHEMBL31442261 0.89 OPRD1 (0.71) OPRM1OPRD1NPBWR1KISS1R
SCHEMBL29822493 0.88 KISS1R (0.65) KISS1R
SCHEMBL29973245 0.87 KISS1R (0.56) OPRM1OPRD1KISS1R
SCHEMBL30690358 0.86 GLP1R (0.66) OPRD1
SCHEMBL31232499 0.86 GLP1R (0.68) NPBWR1KISS1R
SCHEMBL30690385 0.86 OPRM1 (0.61) OPRM1OPRD1NPBWR1KISS1R
SCHEMBL30116700 0.86 PRMT1 (0.61) NPBWR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026107246-A1 SELECTIVE SENOLYTIC CELL PENETRATING PEPTIDE COMPOSITIONS AND USES SENOTHERAPEUTIX, INC. (US) 2026-05-21 — — WO disclosed
EP-4638483-A1 GALANIN-2 RECEPTOR AGONISTS LifeArc (GB) 2025-10-29 — — EP disclosed
US-12263224-B2 Compositions and methods of treating muscle atrophy and myotonic dystrophy AVIDITY BIOSCIENCES, INC. (US) 2025-04-01 — — US disclosed
US-20240327339-A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING VIRAL INFECTIONS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2024-10-03 — — US disclosed
WO-2024132147-A1 GALANIN-2 RECEPTOR AGONISTS LIFEARC (GB) 2024-06-27 — — WO disclosed
WO-2023143610-A2 C-TERMINAL FRAGMENT OF APOLIPOPROTEIN E AND APPLICATION THEREOF IN INHIBITING γ-SECRETASE ACTIVITY 斯莱普泰(上海)生物医药科技有限公司 2023-08-03 — — WO disclosed
US-20230201363-A1 COMPOSITIONS AND METHODS OF TREATING MUSCLE ATROPHY AND MYOTONIC DYSTROPHY AVIDITY BIOSCIENCES, INC. 2023-06-29 — — US disclosed
US-11554176-B2 Compositions and methods of treating muscle atrophy and myotonic dystrophy AVIDITY BIOSCIENCES, INC. (US) 2023-01-17 — — US disclosed
WO-2022170396-A1 AGENTS AND METHODS FOR THERAPY AND PROPHYLAXIS ViraLok Therapeutics Pty Ltd (AU) 2022-08-18 — — WO disclosed
US-20220169680-A1 CELL-PENETRATING PEPTIDE BASED ON INFLUENZA VIRUS M2 PROTEIN INSTITUTE OF BASIC MEDICAL SCIENCES CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2022-06-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12263224-B2 Compositions and methods of treating muscle atrophy and myotonic dystrophy MTPN, MYOF, TNNC1 OPRM1 3028/4885OPRD1 3434/4885NPBWR1 3603/4885
US-11554176-B2 Compositions and methods of treating muscle atrophy and myotonic dystrophy MTPN, MYOF, TNNC1 OPRM1 3028/4885OPRD1 3434/4885NPBWR1 3603/4885
US-20240327339-A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING VIRAL INFECTIONS ACE, ACE2, SARNP OPRM1 2818/4885OPRD1 3335/4885NPBWR1 2808/4885
US-20230201363-A1 COMPOSITIONS AND METHODS OF TREATING MUSCLE ATROPHY AND MYOTONIC DYSTROPHY MTPN, MYOF, TNNC1 OPRM1 3028/4885OPRD1 3434/4885NPBWR1 3603/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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