SCHEMBL2834500

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1337228	0.87	AKR1C2 (0.47)	IKBKBCHUKIKBKEPKMYT1AKR1C2
	SCHEMBL1638704	0.84	IKBKB (0.51)	IKBKBCHUKIKBKEPKMYT1HSD17B10
	SCHEMBL28106449	0.83	METAP2 (0.42)	IKBKBCHUKIKBKEPKMYT1HSD17B10
	SCHEMBL4447987	0.83	HSD17B10 (0.41)	IKBKBCHUKIKBKEPKMYT1HSD17B10
	SCHEMBL29973116	0.83	HSD17B10 (0.41)	IKBKBCHUKIKBKEPKMYT1HSD17B10
	SCHEMBL5016738	0.82	HSD17B10 (0.52)	IKBKBCHUKIKBKEPKMYT1HSD17B10
	SCHEMBL18582910	0.80	NUDT1 (0.45)	IKBKBCHUKIKBKEPKMYT1AKR1C2
	SCHEMBL17841698	0.78	HSD17B10 (0.50)	IKBKBCHUKIKBKEPKMYT1HSD17B10
	SCHEMBL29904187	0.78	HSD17B10 (0.50)	IKBKBCHUKIKBKEPKMYT1HSD17B10
	SCHEMBL3822936	0.78	CA1 (0.43)	AKR1C2AKR1C1HSD17B10ALDH1A1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.