Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | GBA1 | P04062 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23609451 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP3A4THRBALOX15RECQL | |
| SCHEMBL4815674 | 0.80 | ASIC3 (0.54) | ALDH1A1CYP3A4TDP1RAB9AGBA1 | |
| SCHEMBL23609811 | 0.79 | ALDH1A1 (0.51) | ALDH1A1CYP3A4THRBALOX15RECQL | |
| Hydrochloric Acid SCHEMBL4808551 | 0.78 | ASIC3 (0.52) | ALDH1A1CYP3A4TDP1RAB9AGBA1 | |
| SCHEMBL30502777 | 0.77 | CYP3A4 (0.50) | ALDH1A1CYP3A4THRBALOX15RECQL | |
| SCHEMBL25453078 | 0.77 | CYP3A4 (0.50) | ALDH1A1CYP3A4THRBALOX15RECQL | |
| SCHEMBL1702423 | 0.77 | HSD11B1 (0.57) | ALDH1A1CYP3A4HIF1ATDP1RAB9A | |
| SCHEMBL11511767 | 0.76 | CYP3A4 (0.77) | ALDH1A1CYP3A4THRBALOX15RECQL | |
| SCHEMBL23579274 | 0.76 | ALDH1A1 (0.51) | ALDH1A1TDP1RAB9AGBA1TP53 | |
| SCHEMBL29974832 | 0.76 | ALDH1A1 (0.51) | ALDH1A1TDP1RAB9AGBA1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081199-A2 | LIPOXYGENASE INHIBITORS | SRI International (US) | 2022-11-02 | — | — | EP | disclosed |