Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29082974 | 0.90 | MEN1 (0.39) | KMT2AMEN1LMNATHRBBLM | |
| SCHEMBL473072 | 0.84 | ALDH1A1 (0.40) | KMT2AMEN1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7717165 | 0.84 | PTPN1 (0.37) | KMT2AMEN1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8582159 | 0.84 | HPGD (0.40) | LMNAALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL28398309 | 0.83 | LMNA (0.43) | KMT2AMEN1LMNATHRBBLM | |
| SCHEMBL10583374 | 0.82 | CDK4 (0.44) | KMT2AMEN1LMNATHRBBLM | |
| SCHEMBL5490438 | 0.81 | KMT2A (0.41) | KMT2AMEN1LMNATHRBBLM | |
| SCHEMBL9289236 | 0.81 | KMT2A (0.41) | KMT2AMEN1LMNATHRBBLM | |
| SCHEMBL6575512 | 0.81 | C5AR1 (0.35) | KMT2AMEN1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL10715458 | 0.79 | LMNA (0.43) | KMT2AMEN1LMNATHRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 350 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534839-B2 | Sequentially terminated elastomers | BRIDGESTONE CORPORATION (JP) | 2009-05-19 | — | — | US | claimed |
| US-20080071091-A1 | PROCESSES AND COMPOUNDS FOR THE PREPARATION OF SUBSTITUTED NAPHTHYLINDOLE DERIVATIVES | WYETH (US) | 2008-03-20 | — | — | US | claimed |
| EP-0890587-B1 | Amine-initiated elastomers having a hysteresis reducing interaction with silica | BRIDGESTONE CORP (JP) | 2008-03-05 | — | — | EP | claimed |
| US-7323483-B2 | Processes and compounds for the preparation of substituted naphthylindole derivatives | WYETH (US) | 2008-01-29 | — | — | US | claimed |
| EP-1856104-A1 | PROCESSES AND COMPOUNDS FOR THE PREPARATION OF SUBSTITUTED NAPHTHYLINDOLE DERIVATIVES | Wyeth a Corporation of the State of Delaware (US) | 2007-11-21 | — | — | EP | claimed |
| JP-2007500281-A | — | — | 2007-01-11 | — | — | JP | claimed |
| US-20060183917-A1 | Processes and compounds for the preparation of substituted naphthylindole derivatives | WYETH (US) | 2006-08-17 | — | — | US | claimed |
| WO-2006081455-A1 | PROCESSES AND COMPOUNDS FOR THE PREPARATION OF SUBSTITUTED NAPHTHYLINDOLE DERIVATIVES | WYETH (US) | 2006-08-03 | — | — | WO | claimed |
| US-20060135701-A1 | Hysteresis elastomeric compositions comprising sequentially terminated polymers | BRIDGESTONE CORPORATION (JP) | 2006-06-22 | — | — | US | claimed |
| EP-1631596-A1 | IMPROVED HYSTERESIS ELASTOMERIC COMPOSITIONS COMPRISING SEQUENTIALLY TERMINATED POLYMERS | Bridgestone Corporation (JP) | 2006-03-08 | — | — | EP | claimed |
| EP-0718321-A1 | Anionic polymerization initiators and reduced hysteresis products therefrom | BRIDGESTONE CORPORATION (JP) | 1996-06-26 | — | — | EP | claimed |
| WO-1995032243-A1 | POLYPHENYLENE ETHER BLENDS AND PROCESS FOR PRODUCING THEM | OPTATECH CORPORATION (FI) | 1995-11-30 | — | — | WO | claimed |
| EP-0626278-A1 | Solubilized anionic polymerization initiators and products therefrom | BRIDGESTONE CORPORATION (JP) | 1994-11-30 | — | — | EP | claimed |
| EP-0622381-A1 | Anionic polymerization initiators and reduced hysteresis products therefrom | BRIDGESTONE CORPORATION (JP) | 1994-11-02 | — | — | EP | claimed |
| EP-0593049-A1 | Anionic polymerization initiators and reduced hysteresis products therefrom | BRIDGESTONE CORPORATION (JP) | 1994-04-20 | — | — | EP | claimed |
| EP-0590490-A1 | Solubilized anionic polymerization initiators and products therefrom | BRIDGESTONE CORPORATION (JP) | 1994-04-06 | — | — | EP | claimed |
| EP-0299591-B1 | PHOTOPOLYMERISABLE COMPOSITIONS | AUTOTYPE INTERNATIONAL LIMITED (GB) | 1993-01-13 | — | — | EP | claimed |
| US-5043362-A | Polyvinyl alcohol modified with dialkylamino groups as hydrogen donor; screen printing stencils | AUTOTYPE INTERNATIONAL LIMITED (GB) | 1991-08-27 | — | — | US | claimed |
| EP-0299591-A2 | Photopolymerisable compositions | AUTOTYPE INTERNATIONAL LIMITED (GB) | 1989-01-18 | — | — | EP | claimed |
| US-4083827-A | Dialkylaminobenzaldehyde polypyrrolidone composition | CHEVRON RESEARCH COMPANY (US) | 1978-04-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080071091-A1 | PROCESSES AND COMPOUNDS FOR THE PREPARATION OF SUBSTITUTED NAPHTHYLINDOLE DERIVATIVES | SERPINE1, SERPINB1, TFPI | KMT2A 2288/4885MEN1 1364/4885LMNA 737/4885 |
| US-20060183917-A1 | Processes and compounds for the preparation of substituted naphthylindole derivatives | SERPINE1, SERPINB1, TFPI | KMT2A 2288/4885MEN1 1364/4885LMNA 737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.