Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL473072 | 0.84 | ALDH1A1 (0.40) | C5AR1PTPN1POLBKDM4EMEN1 | |
| SCHEMBL7717165 | 0.84 | PTPN1 (0.37) | C5AR1PTPN1POLBKDM4EMEN1 | |
| SCHEMBL11128934 | 0.81 | PTPN1 (0.34) | C5AR1PTPN1POLBKDM4EMEN1 | |
| SCHEMBL299734 | 0.81 | KMT2A (0.44) | C5AR1PTPN1POLBKDM4EMEN1 | |
| SCHEMBL4940765 | 0.77 | NFE2L2 (0.43) | PTPN1POLBKDM4EMEN1KMT2A | |
| SCHEMBL10819024 | 0.77 | HPGD (0.49) | PTPN1KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL10819023 | 0.77 | HPGD (0.49) | PTPN1KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL4940752 | 0.77 | NFE2L2 (0.43) | PTPN1POLBKDM4EMEN1KMT2A | |
| SCHEMBL10583374 | 0.75 | CDK4 (0.44) | C5AR1PTPN1POLBKDM4EMEN1 | |
| SCHEMBL9811806 | 0.74 | NFKB1 (0.47) | PTPN1POLBKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870762-B1 | NOVEL AMINO ACID DERIVATIVES HAVING N,N-DIALKYLAMINOPHENYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2004-04-28 | — | — | EP | disclosed |
| US-5872281-A | COMPOUNDS FOR TREATMENT OF RHEUMATIC DISEASES, PSORIASIS, INTESTINAL INFLAMATION | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0870762-A1 | NOVEL AMINO ACID DERIVATIVES HAVING N,N-DIALKYLAMINOPHENYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |