SCHEMBL29974516

SCHEMBL29974516

COc1cccc(SC)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.58
CYP1A1 P04798 2/20 0.58
CYP1B1 Q16678 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.55
TP53 P04637 1/20 0.55
TSHR P16473 1/20 0.55
RAB9A P51151 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
ACHE P22303 1/20 0.52
ALDH1A1 P00352 2/20 0.50
CYP3A4 P08684 2/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
LMNA P02545 1/20 0.46
CYP2D6 P10635 1/20 0.46
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1145531 1.00 CYP1A2 (0.58) CYP1A2CYP1A1CYP1B1SMN1; SMN2TP53
SCHEMBL28637158 0.84 CYP1A1 (0.42) CYP1A2CYP1A1CYP1B1SMN1; SMN2TP53
SCHEMBL3164341 0.84 ACHE (0.54) ACHEALDH1A1CYP3A4CA1CA2
SCHEMBL31425668 0.84 ACHE (0.54) ACHEALDH1A1CYP3A4CA1CA2
SCHEMBL1157811 0.84 ACHE (0.54) CYP1A2CYP1A1CYP1B1ACHEALDH1A1
SCHEMBL24433577 0.82 ACHE (0.52) ACHEALDH1A1CYP3A4CA1CA2
SCHEMBL1713113 0.80 ACHE (0.50) CYP1A2CYP1A1CYP1B1ACHEALDH1A1
SCHEMBL10709610 0.80 MTNR1A (0.57) CYP1A2CYP1A1CYP1B1ACHEALDH1A1
SCHEMBL644602 0.80 ACHE (0.50) CYP1A2CYP1A1CYP1B1ACHEALDH1A1
SCHEMBL1203595 0.80 ACHE (0.50) CYP1A2CYP1A1CYP1B1ACHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230106223-A1 MOISTURE-CURABLE NON-YELLOWING CLEAR COMPOSITION AND METHOD OF MAKING THEREOFROM MOMENTIVE PERFORMANCE MATERIALS INC. 2023-04-06 US claimed
EP-4081585-A1 MOISTURE-CURABLE NON-YELLOWING CLEAR COMPOSITION AND METHOD OF MAKING THEREOFROM Momentive Performance Materials Inc. (US) 2022-11-02 EP claimed
US-20230106223-A1 MOISTURE-CURABLE NON-YELLOWING CLEAR COMPOSITION AND METHOD OF MAKING THEREOFROM MOMENTIVE PERFORMANCE MATERIALS INC. 2023-04-06 US disclosed
EP-4081585-A1 MOISTURE-CURABLE NON-YELLOWING CLEAR COMPOSITION AND METHOD OF MAKING THEREOFROM Momentive Performance Materials Inc. (US) 2022-11-02 EP disclosed