SCHEMBL644602

SCHEMBL644602

COc1cccc(SBr)c1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.50
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
ALDH1A1 P00352 1/20 0.48
CYP3A4 P08684 1/20 0.48
MTNR1A P48039 7/20 0.45
MTNR1B P49286 7/20 0.45
EDNRA P25101 1/20 0.44
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
ENPP2 Q13822 1/20 0.44
CYP1A1 P04798 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP1B1 Q16678 1/20 0.43
CHRM5 P08912 1/20 0.42
CA4 P22748 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28194454 0.83 ACHE (0.50) ACHECA1CA2CA7CA9
SCHEMBL1603871 0.83 ACHE (0.50) ACHECA1CA2CA7CA9
SCHEMBL31425668 0.82 ACHE (0.54) ACHECA1CA2CA7CA9
SCHEMBL1157811 0.82 ACHE (0.54) ACHECA1CA2CA7CA9
SCHEMBL3164341 0.82 ACHE (0.54) ACHECA1CA2CA7CA9
SCHEMBL24433577 0.80 ACHE (0.52) ACHECA1CA2CA7CA9
SCHEMBL29974516 0.80 CYP1A2 (0.58) ACHECA1CA2CA7CA9
SCHEMBL1145531 0.80 CYP1A2 (0.58) ACHECA1CA2CA7CA9
SCHEMBL14032765 0.79 PARP1 (0.47) ACHECA1CA2CA7CA9
SCHEMBL7059306 0.78 ACHE (0.56) ACHECA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 313 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115651170-A Preparation of heptazine-based polymer and application of heptazine-based polymer in photocatalytic oxidation of thioether 福州大学 2023-01-31 CN claimed
EP-3325443-B1 PROCESS FOR PREPARING PRIDOPIDINE Prilenia Neurotherapeutics Ltd (IL) 2022-06-08 EP claimed
CN-113511997-A Pridopidine analogues, their preparation and use 普丽莱尼亚神经治疗有限公司 2021-10-19 CN claimed
US-10406145-B2 Analogs of pridopidine, their preparation and use PRILENIA NEUROTHERAPEUTICS LTD. (IL) 2019-09-10 US claimed
US-20190030016-A1 ANALOGS OF PRIDOPIDINE, THEIR PREPARATION AND USE TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2019-01-31 US claimed
EP-3325443-A1 PROCESS FOR PREPARING PRIDOPIDINE Teva Pharmaceuticals International GmbH (CH) 2018-05-30 EP claimed
EP-3160470-A1 ANALOGS OF PRIDOPIDINE, THEIR PREPARATION AND USE Teva Pharmaceutical Industries Ltd (IL) 2017-05-03 EP claimed
WO-2017015609-A1 PROCESS FOR PREPARING PRIDOPIDINE TEVA PHARMACEUTICALS INTERNATIONAL GMBH (CH) 2017-01-26 WO claimed
US-20170022158-A1 PROCESS FOR PREPARING PRIDOPIDINE TEVA PHARMACEUTICALS INTERNATIONAL GMBH (CH) 2017-01-26 US claimed
WO-2016003919-A1 ANALOGS OF PRIDOPIDINE, THEIR PREPARATION AND USE TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2016-01-07 WO claimed
US-20250382406-A1 CURABLE COMPOSITION, CURED PRODUCT, OPTICAL MATERIAL, DIFFRACTIVE OPTICAL ELEMENT, AND COMPOUND FUJIFILM CORPORATION (JP) 2025-12-18 US disclosed
EP-4660207-A1 CURABLE COMPOSITION, CURED PRODUCT, OPTICAL MATERIAL, DIFFRACTIVE OPTICAL ELEMENT, AND COMPOUND FUJIFILM Corporation (JP) 2025-12-10 EP disclosed
US-20250277072-A1 CURABLE COMPOSITION, CURED PRODUCT, OPTICAL MATERIAL, DIFFRACTIVE OPTICAL ELEMENT, AND MONOFUNCTIONAL (METH)ACRYLIC ACID THIOESTER MONOMER FUJIFILM CORPORATION (JP) 2025-09-04 US disclosed
EP-4565586-A1 NOVEL ECTONUCLEOTIDE PYROPHOSPHATASE / PHOSPHODIESTERASE 1 (ENPP-1) INHIBITORS AND USES THEREOF Sravathi Ai Technology Private Limited (IN) 2025-06-11 EP disclosed
CN-119677742-A Novel external nucleotide pyrophosphatase/phosphodiesterase 1 (ENPP 1) inhibitor and application thereof 斯拉瓦蒂人工智能科技私人有限公司 2025-03-21 CN disclosed
US-5130316-A Arylbenzene oxazolidinone compounds DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1992-07-14 US disclosed
US-5043443-A Bactericides DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1991-08-27 US disclosed
US-4948801-A Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-08-14 US disclosed
US-4900725-A CONTRACEPTIVES ROUSSEL UCLAF (FR) 1990-02-13 US disclosed
EP-0252639-A1 Leukotriene antagonists MERCK FROSST CANADA INC. (CA) 1988-01-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10406145-B2 Analogs of pridopidine, their preparation and use QDPR, DRD2, OPRD1 ACHE 2752/4885CA1 4389/4885CA2 2324/4885
US-20170022158-A1 PROCESS FOR PREPARING PRIDOPIDINE PDE6D, QDPR, PDE4D ACHE 4017/4885CA1 4777/4885CA2 4397/4885
US-20250382406-A1 CURABLE COMPOSITION, CURED PRODUCT, OPTICAL MATERIAL, DIFFRACTIVE OPTICAL ELEMENT, AND COMPOUND C5, Q6ZSR9, C9 ACHE 1073/4885CA1 1465/4885CA2 3634/4885
US-20250277072-A1 CURABLE COMPOSITION, CURED PRODUCT, OPTICAL MATERIAL, DIFFRACTIVE OPTICAL ELEMENT, AND MONOFUNCTIONAL (METH)ACRYLIC ACID THIOESTER MONOMER CAD, ADCY1, AMD1 ACHE 1694/4885CA1 1180/4885CA2 4225/4885
US-20190030016-A1 ANALOGS OF PRIDOPIDINE, THEIR PREPARATION AND USE QDPR, DRD2, OPRD1 ACHE 2752/4885CA1 4389/4885CA2 2324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.