Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 6/20 | 0.52 |
| ▸ | NLRP3 | Q96P20 | 8/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29326150 | 1.00 | IL1B (0.52) | IL1BNLRP3TRPV1HDAC4HDAC6 | |
| SCHEMBL29326149 | 1.00 | IL1B (0.52) | IL1BNLRP3TRPV1HDAC4HDAC6 | |
| SCHEMBL29326121 | 0.95 | IL1B (0.47) | IL1BNLRP3TRPV1HDAC4HDAC6 | |
| SCHEMBL27182184 | 0.91 | IL1B (0.49) | IL1BNLRP3TRPV1HDAC4HDAC6 | |
| SCHEMBL29155911 | 0.90 | TRPV1 (0.43) | IL1BNLRP3TRPV1HDAC4HDAC6 | |
| SCHEMBL30684797 | 0.90 | TRPV1 (0.43) | IL1BNLRP3TRPV1HDAC4HDAC6 | |
| SCHEMBL27182188 | 0.89 | IL1B (0.56) | IL1BNLRP3KCNH2 | |
| SCHEMBL31057291 | 0.87 | IL1B (0.70) | IL1BNLRP3TRPV1HDAC4HDAC6 | |
| SCHEMBL29326142 | 0.86 | IL1B (0.44) | IL1BNLRP3HDAC4HDAC6MAPT | |
| SCHEMBL29326123 | 0.86 | NLRP3 (0.46) | IL1BNLRP3HDAC4HDAC6IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022230912-A1 | SUBSTITUTED TRIAZINE COMPOUND | アステラス製薬株式会社 | 2022-11-03 | — | — | WO | disclosed |