Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 4/20 | 0.47 |
| ▸ | IDH1 | O75874 | 2/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 2/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | IDH2 | P48735 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29974698 | 0.95 | IL1B (0.52) | IL1BIDH1NLRP3HDAC4HDAC6 | |
| SCHEMBL29326149 | 0.95 | IL1B (0.52) | IL1BIDH1NLRP3HDAC4HDAC6 | |
| SCHEMBL29326150 | 0.95 | IL1B (0.52) | IL1BIDH1NLRP3HDAC4HDAC6 | |
| SCHEMBL29326123 | 0.89 | NLRP3 (0.46) | IL1BIDH1NLRP3SCN9AHDAC4 | |
| SCHEMBL27182184 | 0.88 | IL1B (0.49) | IL1BNLRP3HDAC4HDAC6BTK | |
| SCHEMBL29326289 | 0.85 | NLRP3 (0.42) | IL1BIDH1NLRP3SYKIDH2 | |
| SCHEMBL30684761 | 0.85 | IL1B (0.43) | IL1BIDH1NLRP3SYKJAK2 | |
| SCHEMBL27182172 | 0.85 | IL1B (0.43) | IL1BIDH1NLRP3SYKJAK2 | |
| SCHEMBL29326283 | 0.85 | NLRP3 (0.42) | IL1BIDH1NLRP3SYKIDH2 | |
| SCHEMBL29155911 | 0.85 | TRPV1 (0.43) | IL1BIDH1NLRP3SCN9AHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239758-A1 | SUBSTITUTED TRIAZINE COMPOUND | NICO THERAPEUTICS, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239758-A1 | SUBSTITUTED TRIAZINE COMPOUND | NLRP3, NLRP1, PYCARD | IL1B 11/4885IDH1 2485/4885NLRP3 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.