Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 4/20 | 0.44 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 2/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KAT7 | O95251 | 1/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29326847 | 0.90 | IL1B (0.47) | IL1BNLRP3CCNT1 | |
| SCHEMBL29974698 | 0.86 | IL1B (0.52) | IL1BNLRP3HDAC4HDAC6MAPT | |
| SCHEMBL29326150 | 0.86 | IL1B (0.52) | IL1BNLRP3HDAC4HDAC6MAPT | |
| SCHEMBL29326149 | 0.86 | IL1B (0.52) | IL1BNLRP3HDAC4HDAC6MAPT | |
| SCHEMBL29326138 | 0.86 | TRPV1 (0.44) | IL1BNLRP3 | |
| SCHEMBL29326156 | 0.85 | NLRP3 (0.41) | IL1BNLRP3SCN9AHDAC4HDAC6 | |
| SCHEMBL29326121 | 0.85 | IL1B (0.47) | IL1BNLRP3SCN9AHDAC4HDAC6 | |
| SCHEMBL29326123 | 0.81 | NLRP3 (0.46) | IL1BNLRP3SCN9AHDAC4HDAC6 | |
| SCHEMBL29326670 | 0.80 | NLRP3 (0.54) | IL1BNLRP3 | |
| SCHEMBL25405494 | 0.80 | IL1B (0.42) | IL1BIRAK1NLRP3ACKR3GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239758-A1 | SUBSTITUTED TRIAZINE COMPOUND | NICO THERAPEUTICS, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239758-A1 | SUBSTITUTED TRIAZINE COMPOUND | NLRP3, NLRP1, PYCARD | IL1B 11/4885IRAK1 37/4885NLRP3 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.