Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL2992348 | 0.83 | ALOX5AP (0.41) | ALOX5AP | |
| Ammonia Solution, Strong SCHEMBL3005507 | 0.81 | ALOX5AP (0.54) | ALOX5AP | |
| SCHEMBL3002980 | 0.78 | APP (0.45) | ACACBALOX5APMMP9MMP13ADAM17 | |
| SCHEMBL3000902 | 0.77 | ALOX5AP (0.43) | ACACBALOX5APCYSLTR2CYSLTR1MMP9 | |
| SCHEMBL3000188 | 0.76 | ACACB (0.46) | ACACBALOX5APALOX5 | |
| SCHEMBL2995628 | 0.76 | NPC1 (0.46) | ACACBALOX5AP | |
| SCHEMBL2999090 | 0.75 | ALOX5AP (0.48) | ACACBALOX5APCYSLTR2CYSLTR1MMP9 | |
| SCHEMBL3002131 | 0.75 | ALOX5AP (0.59) | ACACBALOX5APCYSLTR2CYSLTR1MMP9 | |
| SCHEMBL3000148 | 0.75 | AOC3 (0.41) | — | |
| SCHEMBL2993269 | 0.75 | NR4A2 (0.49) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010038953-A2 | URACIL-BASED COMPOUNDS, AND HERBICIDES COMPRISING SAME | 한국화학연구원 (KR) | 2010-04-08 | — | — | WO | claimed |
| US-20100190761-A1 | DIPHENYL SUBSTITUTED ALKANES | MERCK SHARP & DOHME CORP. | 2010-07-29 | — | — | US | disclosed |
| WO-2010038953-A2 | URACIL-BASED COMPOUNDS, AND HERBICIDES COMPRISING SAME | 한국화학연구원 (KR) | 2010-04-08 | — | — | WO | disclosed |
| EP-2170065-A1 | DIPHENYL SUBSTITUTED ALKANES | Merck Sharp & Dohme Corp. (US) | 2010-04-07 | — | — | EP | disclosed |
| WO-2008156721-A1 | DIPHENYL SUBSTITUTED ALKANES | MERCK & CO., INC. (US) | 2008-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190761-A1 | DIPHENYL SUBSTITUTED ALKANES | ALOX5, ALOX15, ALOX15B | ACACB 1284/4885ALOX5AP 15/4885CYSLTR2 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.