SCHEMBL29975337

SCHEMBL29975337

CCN(CC)CC.CCN(CC)CC.O=C(Nc1ccn([C@H]2CN(C(c3ccccc3)(c3ccccc3)c3ccccc3)C[C@@H](CP(=O)(O)O)O2)c(=O)n1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.53
RIN1 Q13671 1/20 0.53
P2RY6 Q15077 16/20 0.52
P2RY14 Q15391 2/20 0.52
POLB P06746 1/20 0.46
NT5E P21589 1/20 0.44
P2RY2 P41231 3/20 0.37
P2RY4 P51582 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27158214 0.94 ABL1 (0.59) ABL1RIN1P2RY6P2RY14POLB
SCHEMBL29975237 0.90 P2RY6 (0.49) ABL1RIN1P2RY6P2RY14POLB
SCHEMBL27158019 0.86 ABL1 (0.47) ABL1RIN1P2RY6P2RY14POLB
SCHEMBL14980414 0.85 ABL1 (0.70) ABL1RIN1P2RY6P2RY14POLB
SCHEMBL15090413 0.85 ABL1 (0.70) ABL1RIN1P2RY6P2RY14POLB
SCHEMBL29975465 0.85 ABL1 (0.48) ABL1RIN1P2RY6P2RY14POLB
SCHEMBL23565661 0.84 ABL1 (0.61) ABL1RIN1P2RY6P2RY14POLB
SCHEMBL23607152 0.84 ABL1 (0.56) ABL1RIN1P2RY6P2RY14POLB
SCHEMBL30937947 0.84 ABL1 (0.53) ABL1RIN1P2RY6P2RY14POLB
SCHEMBL21361135 0.84 ABL1 (0.53) ABL1RIN1P2RY6P2RY14POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240254158-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND NIPPON SHINYAKU CO., LTD. (JP) 2024-08-01 US disclosed
EP-4332111-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND Nippon Shinyaku Co., Ltd. (JP) 2024-03-06 EP disclosed
WO-2022230954-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND 日本新薬株式会社 2022-11-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240254158-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND POLRMT, CYC1, MRM1 ABL1 3283/4885RIN1 3783/4885P2RY6 3552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.