Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ASPH | Q12797 | 1/20 | 0.42 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 2/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.38 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.36 |
| ▸ | SELL | P14151 | 1/20 | 0.35 |
| ▸ | SELP | P16109 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL318609 | 1.00 | CES2 (0.45) | CES2CES1KDM4EASPHKDM8 | |
| SCHEMBL31094955 | 0.84 | CYP1A2 (0.44) | CES2CES1KDM4EASPHKDM8 | |
| SCHEMBL7558115 | 0.83 | CES2 (0.50) | CES2CES1KDM4EASPHKDM8 | |
| SCHEMBL4851530 | 0.83 | KDM4E (0.42) | CES2CES1KDM4EASPHKDM8 | |
| SCHEMBL24717969 | 0.81 | CYP1A2 (0.41) | CES2CES1KDM4EASPHKDM8 | |
| SCHEMBL30827695 | 0.81 | DGAT1 (0.55) | CES2CES1KDM4EDGAT1MAP2K1 | |
| SCHEMBL28221635 | 0.81 | ALDH1A1 (0.47) | CES2CES1DGAT1SMN1; SMN2ALDH1A1 | |
| SCHEMBL241797 | 0.79 | CES2 (0.70) | CES2CES1KDM4EASPHKDM8 | |
| SCHEMBL31225023 | 0.79 | KDM4E (0.40) | KDM4EASPHKDM8CYP1A2TSHR | |
| SCHEMBL1671271 | 0.79 | KDM4E (0.40) | KDM4EASPHKDM8CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073282-A | Method for rapidly preparing 3-bromo-2, 4-difluorobenzoic acid based on microchannel continuous flow technology | 都创(重庆)医药科技有限公司 | 2022-09-20 | — | — | CN | claimed |
| EP-4714939-A1 | SULFONAMIDE COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | Shenzhen Salubris Pharmaceuticals Co., Ltd. (CN) | 2026-03-25 | — | — | EP | disclosed |
| CN-120035578-A | Sulfonamide compound, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2025-05-23 | — | — | CN | disclosed |
| CN-112543764-B | Amide compound with BET proteolytic induction effect and medical application thereof | 田边三菱制药株式会社 | 2024-05-10 | — | — | CN | disclosed |
| CN-116261562-A | PI 3K-alpha inhibitors and methods of use thereof | 传达治疗有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-115073282-A | Method for rapidly preparing 3-bromo-2, 4-difluorobenzoic acid based on microchannel continuous flow technology | 都创(重庆)医药科技有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-115073282-A | Method for rapidly preparing 3-bromo-2, 4-difluorobenzoic acid based on microchannel continuous flow technology | 都创(重庆)医药科技有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-115073282-A | Method for rapidly preparing 3-bromo-2, 4-difluorobenzoic acid based on microchannel continuous flow technology | 都创(重庆)医药科技有限公司 | 2022-09-20 | — | — | CN | disclosed |