Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.42 |
| ▸ | CDK2 | P24941 | 4/20 | 0.42 |
| ▸ | AHCY | P23526 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 3/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21853761 | 1.00 | ALDH1A1 (0.44) | ALDH1A1CCNE1CDK2AHCYCYP2C19 | |
| SCHEMBL21853756 | 1.00 | ALDH1A1 (0.44) | ALDH1A1CCNE1CDK2AHCYCYP2C19 | |
| SCHEMBL7271581 | 0.86 | CCNE1 (0.44) | ALDH1A1CCNE1CDK2CYP2C19HDAC6 | |
| SCHEMBL7271567 | 0.86 | CCNE1 (0.44) | ALDH1A1CCNE1CDK2CYP2C19HDAC6 | |
| SCHEMBL25875455 | 0.73 | CYP2C19 (0.50) | CCNE1CDK2CYP2C19CDK1CCNB1 | |
| SCHEMBL17860490 | 0.72 | CCNE1 (0.71) | CCNE1CDK2CYP2C19CDK1CCNB1 | |
| SCHEMBL7272071 | 0.72 | CCNE1 (0.43) | ALDH1A1CCNE1CDK2CYP2C19HDAC6 | |
| SCHEMBL7272082 | 0.72 | CCNE1 (0.43) | ALDH1A1CCNE1CDK2CYP2C19HDAC6 | |
| Omaciclovir SCHEMBL14569460 | 0.72 | CCNE1 (0.43) | ALDH1A1CCNE1CDK2AHCYCYP2C19 | |
| SCHEMBL20577001 | 0.72 | CCNE1 (0.45) | CCNE1CDK2AHCYCYP2C19HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630795-B1 | ENGINEERED ALDOLASE POLYPEPTIDES AND USES THEREOF | ENZYMASTER NINGBO BIO ENG CO LTD (CN) | 2023-07-26 | — | — | EP | disclosed |
| CN-110869383-B | Engineered polypeptides and their use in the synthesis of beta-hydroxy-alpha-amino acids | 宁波酶赛生物工程有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-110914288-B | Engineered aldolase polypeptides and uses thereof | 宁波酶赛生物工程有限公司 | 2023-05-05 | — | — | CN | disclosed |
| US-11512303-B2 | Engineered polypeptides and their applications in the synthesis of beta-hydroxy-alpha-amino acids | ENZYMASTER (NINGBO) BIO-ENGINEERING CO., LTD. (CN) | 2022-11-29 | — | — | US | disclosed |
| EP-3630798-B1 | ENGINEERED ALDOLASE POLYPEPTIDES AND THEIR APPLICATIONS IN SYNTHESIS OF BETA-HYDROXY-ALPHA-AMINO ACIDS | ENZYMASTER NINGBO BIO ENG CO LTD (CN) | 2022-11-23 | — | — | EP | disclosed |