Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27769567 | 0.78 | EPHX2 (0.46) | BLMPTPN1EPHX2NR1H4ENPP2 | |
| SCHEMBL8133933 | 0.77 | ENPP2 (0.48) | PTPN1EPHX2NR1H4ENPP2AKR1C3 | |
| SCHEMBL17768418 | 0.77 | BLM (0.65) | BLMSMN1; SMN2HIF1AKDM4EPTGS2 | |
| SCHEMBL28966331 | 0.77 | BLM (0.65) | BLMSMN1; SMN2HIF1AKDM4EPTGS2 | |
| SCHEMBL2336417 | 0.76 | SMN1; SMN2 (0.67) | BLMSMN1; SMN2HIF1A | |
| SCHEMBL17498702 | 0.76 | SMN1; SMN2 (0.67) | BLMSMN1; SMN2HIF1A | |
| SCHEMBL16816903 | 0.76 | SMN1; SMN2 (0.67) | BLMSMN1; SMN2HIF1A | |
| SCHEMBL19953750 | 0.75 | PTPN1 (0.42) | PTPN1EPHX2NR1H4ENPP2PTGDR2 | |
| Acetone SCHEMBL12483000 | 0.75 | SMN1; SMN2 (0.60) | BLMSMN1; SMN2HIF1A | |
| SCHEMBL6606841 | 0.75 | EPHX2 (0.46) | PTPN1EPHX2NR1H4ENPP2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11512303-B2 | Engineered polypeptides and their applications in the synthesis of beta-hydroxy-alpha-amino acids | ENZYMASTER (NINGBO) BIO-ENGINEERING CO., LTD. (CN) | 2022-11-29 | — | — | US | disclosed |
| EP-3630798-B1 | ENGINEERED ALDOLASE POLYPEPTIDES AND THEIR APPLICATIONS IN SYNTHESIS OF BETA-HYDROXY-ALPHA-AMINO ACIDS | ENZYMASTER NINGBO BIO ENG CO LTD (CN) | 2022-11-23 | — | — | EP | disclosed |