Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 2/20 | 0.35 |
| ▸ | ALPI | P09923 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29976519 | 0.77 | PKM (0.43) | HRH4PKMALPLALPIF10 | |
| SCHEMBL29976300 | 0.76 | SDHB (0.56) | MEN1KMT2AALDH1A1POLBNPSR1 | |
| SCHEMBL18049941 | 0.72 | LOXL2 (0.43) | HRH4PKMALPLALPIPOLB | |
| SCHEMBL18050118 | 0.72 | ALPL (0.43) | HRH4PKMALPLALPIMEN1 | |
| Hydrochloric Acid SCHEMBL18050080 | 0.71 | LOXL2 (0.43) | HRH4PKMALPLALPIPOLB | |
| SCHEMBL18072284 | 0.69 | PKM (0.39) | HRH4PKMALPLALPIMEN1 | |
| SCHEMBL29976432 | 0.68 | NPSR1 (0.55) | MEN1KMT2ANPSR1HPGDLMNA | |
| SCHEMBL19805966 | 0.68 | NPSR1 (0.55) | MEN1KMT2ANPSR1HPGDLMNA | |
| SCHEMBL19805804 | 0.67 | SDHB (0.48) | DRD2DRD3SDHB | |
| SCHEMBL1041295 | 0.65 | F10 (0.42) | F10CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |