Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 7/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | P4HB | P07237 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2997703 | 1.00 | ALDH1A1 (0.49) | ALDH1A1KMT2AMAPTMAPK1KDM4E | |
| SCHEMBL3006047 | 0.89 | ACHE (0.53) | ALDH1A1KMT2AMAPTMAPK1KDM4E | |
| SCHEMBL3006044 | 0.89 | ACHE (0.53) | ALDH1A1KMT2AMAPTMAPK1KDM4E | |
| SCHEMBL2997702 | 0.89 | KMT2A (0.38) | ALDH1A1KMT2AMAPTMAPK1KDM4E | |
| SCHEMBL2997704 | 0.89 | KMT2A (0.38) | ALDH1A1KMT2AMAPTMAPK1KDM4E | |
| SCHEMBL3005167 | 0.83 | MAPT (0.50) | ALDH1A1KMT2AMAPTMAPK1KDM4E | |
| SCHEMBL3006675 | 0.83 | LMNA (0.51) | ALDH1A1KMT2AMAPTMAPK1KDM4E | |
| SCHEMBL3006677 | 0.83 | LMNA (0.51) | ALDH1A1KMT2AMAPTMAPK1KDM4E | |
| SCHEMBL3005164 | 0.83 | MAPT (0.50) | ALDH1A1KMT2AMAPTMAPK1KDM4E | |
| SCHEMBL2999863 | 0.79 | MAPT (0.69) | ALDH1A1KMT2AMAPTMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190824-A1 | Novel Substituted Piperidones as HSP Inducers | TORRENT PHARMACEUTICALS LTD. (IN) | 2010-07-29 | — | — | US | claimed |
| US-20100190824-A1 | Novel Substituted Piperidones as HSP Inducers | TORRENT PHARMACEUTICALS LTD. (IN) | 2010-07-29 | — | — | US | disclosed |
| EP-2178835-A1 | NOVEL SUBSTITUTED PIPERIDONES AS HSP INDUCERS | Torrent Pharmaceuticals Ltd (IN) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009004650-A1 | NOVEL SUBSTITUTED PIPERIDONES AS HSP INDUCERS | TORRENT PHARMACEUTICALS LTD. (IN) | 2009-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190824-A1 | Novel Substituted Piperidones as HSP Inducers | HSF1, HSPA4, HSPA5 | ALDH1A1 541/4885KMT2A 4596/4885MAPT 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.